Lessons from the host defences of bats, a unique viral reservoir

AT Irving, M Ahn, G Goh, DE Anderson, LF Wang - Nature, 2021 - nature.com
There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …

Horizons in the evolution of aging

T Flatt, L Partridge - BMC biology, 2018 - Springer
Between the 1930s and 50s, evolutionary biologists developed a successful theory of why
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …

Evolutionary constraint and innovation across hundreds of placental mammals

MJ Christmas, IM Kaplow, DP Genereux, MX Dong… - Science, 2023 - science.org
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host

M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim… - Nature …, 2019 - nature.com
Bats are special in their ability to host emerging viruses. As the only flying mammal, bats
endure high metabolic rates yet exhibit elongated lifespans. It is currently unclear whether …

[图书][B] Bats in the Anthropocene

CC Voigt, T Kingston - 2016 - library.oapen.org
Humans have inadvertently changed global ecosystems and triggered the dawn of a new
geological epoch, the Anthropocene. While some organisms can tolerate human activities …

Bats as 'special'reservoirs for emerging zoonotic pathogens

CE Brook, AP Dobson - Trends in microbiology, 2015 - cell.com
The ongoing West African Ebola epidemic highlights a recurring trend in the zoonotic
emergence of virulent pathogens likely to come from bat reservoirs that has caused …

The functional roles of mammals in ecosystems

TE Lacher Jr, AD Davidson, TH Fleming… - Journal of …, 2019 - academic.oup.com
The diverse functional roles of over 6,000 species of extant mammals that range in body size
across eight orders of magnitude, from blue whales (Balaenoptera musculus) to tiny …

[HTML][HTML] The world goes bats: living longer and tolerating viruses

V Gorbunova, A Seluanov, BK Kennedy - Cell Metabolism, 2020 - cell.com
For centuries, people believed that bats possessed sinister powers. Bats are thought to be
ancestral hosts to many deadly viruses affecting humans including Ebola, rabies, and most …

Bats and zoonotic viruses: can we confidently link bats with emerging deadly viruses?

R Moratelli, CH Calisher - Memórias do Instituto Oswaldo Cruz, 2015 - SciELO Brasil
An increasingly asked question is' can we confidently link bats with emerging viruses?'. No,
or not yet, is the qualified answer based on the evidence available. Although more than 200 …

Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases

M Ahn, VCW Chen, P Rozario, WL Ng, P San Kong… - Cell, 2023 - cell.com
Bats are special in their ability to live long and host many emerging viruses. Our previous
studies showed that bats have altered inflammasomes, which are central players in aging …