Characterizing natural recovery after traumatic spinal cord injury

S Kirshblum, B Snider, F Eren, J Guest - Journal of neurotrauma, 2021 - liebertpub.com
The predominant tool used to predict outcomes after traumatic spinal cord injury (SCI) is the
International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI), in …

From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

[HTML][HTML] Antioxidant therapies in traumatic brain and spinal cord injury

M Bains, ED Hall - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2012 - Elsevier
Free radical formation and oxidative damage have been extensively investigated and
validated as important contributors to the pathophysiology of acute central nervous system …

[HTML][HTML] Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical …

JW Fawcett, A Curt, JD Steeves, WP Coleman… - Spinal cord, 2007 - nature.com
Abstract The International Campaign for Cures of Spinal Cord Injury Paralysis (ICCP)
supported an international panel tasked with reviewing the methodology for clinical trials in …

[HTML][HTML] Axon growth inhibition by RhoA/ROCK in the central nervous system

Y Fujita, T Yamashita - Frontiers in neuroscience, 2014 - frontiersin.org
Rho kinase (ROCK) is a serine/threonine kinase and a downstream target of the small
GTPase Rho. The RhoA/ROCK pathway is associated with various neuronal functions such …

A clinical prediction rule for ambulation outcomes after traumatic spinal cord injury: a longitudinal cohort study

JJ van Middendorp, AJF Hosman, ART Donders… - The Lancet, 2011 - thelancet.com
Background Traumatic spinal cord injury is a serious disorder in which early prediction of
ambulation is important to counsel patients and to plan rehabilitation. We developed a …

Efficacy of virtual reality rehabilitation after spinal cord injury: a systematic review

AVL De Araújo, JFO Neiva… - BioMed research …, 2019 - Wiley Online Library
Background. Spinal cord injury (SCI) is often associated with long‐term impairments related
to functional limitations in the sensorimotor system. The use of virtual reality (VR) technology …

Corticospinal-motor neuronal plasticity promotes exercise-mediated recovery in humans with spinal cord injury

HJ Jo, MA Perez - Brain, 2020 - academic.oup.com
Rehabilitative exercise in humans with spinal cord injury aims to engage residual neural
networks to improve functional recovery. We hypothesized that exercise combined with non …

The influence of time from injury to surgery on motor recovery and length of hospital stay in acute traumatic spinal cord injury: an observational Canadian cohort study

MF Dvorak, VK Noonan, N Fallah, CG Fisher… - Journal of …, 2015 - liebertpub.com
To determine the influence of time from injury to surgery on neurological recovery and length
of stay (LOS) in an observational cohort of individuals with traumatic spinal cord injury (tSCI) …

Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial

A Mackay-Sim, F Feron, J Cochrane… - Brain, 2008 - academic.oup.com
Olfactory ensheathing cells show promise in preclinical animal models as a cell
transplantation therapy for repair of the injured spinal cord. This is a report of a clinical trial of …