Current perspectives on corneal collagen crosslinking (CXL)

SK Subasinghe, KC Ogbuehi, GJ Dias - Graefe's Archive for Clinical and …, 2018 - Springer
Corneal collagen crosslinking has revolutionized the treatment of keratoconus and post-
refractive corneal ectasia in the past decade. Corneal crosslinking with riboflavin and …

Corneal crosslinking in keratoconus management

S Saad, R Saad, L Jouve, S Kallel, L Trinh… - Journal Français d' …, 2020 - Elsevier
Since two decades, corneal crosslinking (CXL) has been proposed as the sole therapeutic
option to halt progression of keratoconus or other ectatic diseases. CXL aims at stiffening the …

Longitudinal assessment of the effect of alkali burns on corneal biomechanical properties using optical coherence elastography

T Mekonnen, X Lin, C Zevallos‐Delgado… - Journal of …, 2022 - Wiley Online Library
Eye injury due to alkali burn is a severe ocular trauma that can profoundly affect corneal
structure and function, including its biomechanical properties. Here, we assess the changes …

Cost-effectiveness analysis of corneal collagen crosslinking for progressive keratoconus

DA Godefrooij, MJJ Mangen, E Chan, DPS O'Brart… - Ophthalmology, 2017 - Elsevier
Purpose To evaluate the cost effectiveness of corneal collagen crosslinking (CXL) for
progressive keratoconus from the healthcare payer's perspective. Design A probabilistic …

Crosslinking with UV-A and riboflavin in progressive keratoconus: From laboratory to clinical practice–developments over 25 years

F Raiskup, R Herber, J Lenk, LE Pillunat… - Progress in Retinal and …, 2024 - Elsevier
Abstract Changes in the biomechanical and biochemical properties of the human cornea
play an important role in the pathogenesis of ectatic diseases. A number of conditions in …

Collagen V insufficiency in a mouse model for Ehlers Danlos-syndrome affects viscoelastic biomechanical properties explaining thin and brittle corneas

S Kling, EA Torres-Netto, H Abdshahzadeh… - Scientific Reports, 2021 - nature.com
Ehlers–Danlos syndrome (EDS) is a genetic disease leading to abnormalities in mechanical
properties of different tissues. Here we quantify corneal biomechanical properties in an adult …

Clinical results of repeated corneal collagen cross-linking in progressive keratoconus

SA Turhan, FO Aydın, E Toker - Cornea, 2020 - journals.lww.com
Purpose: To evaluate the effectiveness of repeated corneal collagen cross-linking (CXL) in
eyes with progressive keratoconus after primary CXL. Methods: Twelve eyes of 10 patients …

Corneal biomechanical stiffness and histopathological changes after in vivo repeated accelerated corneal cross-linking in cat eyes

X Zhang, L Sun, L Chen, C Zhang, Y Xian… - Experimental Eye …, 2023 - Elsevier
Corneal cross-linking (CXL) has been proved efficiency for treating progressive keratoconus
and other corneal ectasia diseases by stabilizing corneal geometry and biomechanics …

Safety and efficacy of repeated crosslinking assisted by transepithelial double-cycle iontophoresis in keratoconus progression after primary corneal crosslinking

H Wu, L Li, S Luo, X Fang, X Shang, Z Xie, X Xiao… - Eye, 2021 - nature.com
Objectives To evaluate the safety and efficacy of repeated corneal collagen crosslinking
assisted by transepithelial double-cycle iontophoresis (DI-CXL) in the management of …

Crosslinking‐Induced Corneal Endothelium Dysfunction and Its Protection by Topical Ripasudil Treatment

X Wang, Y Zhong, M Liang, Z Lin, H Wu… - Disease Markers, 2022 - Wiley Online Library
Purpose. To investigate the changes of corneal endothelium under different crosslinking
conditions and the protective effect of ripasudil. Methods. Corneal crosslinking groups were …