Thyroid hormone synthesis requires adequate hydrogen peroxide (H2O2) production that is
utilized as an oxidative agent during the synthesis of thyroxin (T4) and triiodothyronine (T3) …

Thyroid cancer is a common endocrine malignancy with increasing incidence globally.
Although most cases can be treated effectively, some cases are more aggressive and have …

The pentose phosphate pathway (PPP) plays an important role in the biosynthesis of
ribonucleotide precursor and NADPH. Cancer cells frequently increase the flux of glucose …

Metabolism is a series of life-sustaining chemical reactions in organisms, providing energy
required for cellular processes and building blocks for cellular constituents of proteins, lipids …

Thyroid cancers (TCs) are the most frequent endocrine malignancy with an unpredictable
fast-growing incidence, especially in females all over the world. Fine-needle aspiration …

Among all the adaptations of cancer cells, their ability to change metabolism from the
oxidative to the glycolytic phenotype is a hallmark called the Warburg effect. Studies on …

Purpose Our previous study demonstrated that SIRT6 is upregulated in papillary thyroid
cancer (PTC) and enhances tumor aggressiveness. In this study, we further researched its …

In Hashimoto's thyroiditis (HT), oxidative stress (OS) is driven by Th1 cytokines' response
interfering with the normal function of thyrocytes. OS results from an imbalance between an …

Papillary thyroid carcinoma (PTC) is the common subtype of thyroid cancer, which is a
common endocrine malignancy. Tripartite motif 26 (TRIM26) has been found to act as a …

Purpose: Thyroid cancer metabolic characteristics vary depending on the molecular subtype
determined by mutational status. We aimed to investigate the molecular subtype-specific …