Obsessive-compulsive disorder (OCD) is a serious and often chronically disabling condition. The current dominant model of OCD focuses on abnormalities in prefrontal-striatal circuits …
The word 'addiction'these days is used to refer to a chronic condition where there is an unhealthily powerful motivation to engage in a particular behaviour. This can be driven by …
Obsessive-compulsive disorder (OCD) is a common, heritable and disabling neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …
M Del Giudice - Psychological Inquiry, 2014 - Taylor & Francis
In this article, I outline a general framework for the evolutionary analysis of mental disorders based on the concepts of life history theory. I synthesize and extend a large body of work …
SR Chamberlain, AD Blackwell, NA Fineberg… - Neuroscience & …, 2005 - Elsevier
Obsessive compulsive disorder (OCD) is a highly debilitating neuropsychiatric condition with estimated lifetime prevalence of 2–3%, more than twice that of schizophrenia. However, in …
Endophenotypes (intermediate phenotypes) are objective, heritable, quantitative traits hypothesized to represent genetic risk for polygenic disorders at more biologically tractable …
R Penades, R Catalan, K Rubia, S Andrés… - European …, 2007 - cambridge.org
ObjectiveThe present study investigates different three inhibitory control functions in patients with obsessive-compulsive disorder (OCD). Selective motor response inhibition was tested …
The activity of neurons in the brain is noisy in that their firing times are random when they are firing at a given mean rate. This introduces a random or stochastic property into brain …
Aims Addiction has been conceptualized as a shift from controlled experimentation to uncontrolled, compulsive patterns of use. Current neurobiological models of addiction …