Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …

The closure of gaps is crucial to maintaining epithelium integrity during developmental and
repair processes such as dorsal closure and wound healing. Depending on biochemical as …

Fundamental biological processes are carried out by curved epithelial sheets that enclose a
pressurized lumen. How these sheets develop and withstand three-dimensional …

The collective behaviour of cells in epithelial tissues is dependent on their mechanical
properties. However, the contribution of tissue mechanics to wound healing in vivo remains …

Planar in vitro models have been invaluable tools to identify the mechanical basis of wound
closure. Although these models may recapitulate closure dynamics of epithelial cell sheets …

Apoptotic extrusion is crucial in maintaining epithelial homeostasis. Current literature
supports that epithelia respond to extrusion by forming a supracellular actomyosin purse …

The collective dynamics of multicellular systems arise from the interplay of a few
fundamental elements: growth, division and apoptosis of single cells; their mechanical and …

Wound healing through reepithelialization of gaps is of profound importance to the medical
community. One critical mechanism identified by researchers for closing non-cell-adhesive …

Adhesive micropatterns have become a standard tool to study cells under defined
conditions. Applications range from controlling the differentiation and fate of single cells to …

The cellular uptake of nanoparticles or viruses requires that the gain of adhesion energy
overcomes the cost of plasma membrane bending. It is well known that this leads to a …