Alzheimer's disease (AD) is well-known as a severe neurodegeneration disease involving
complicated etiologies, and cholinesterase inhibition remain the prevailing mode of clinical …

The link between histopathological hallmarks of Alzheimer's disease (AD), ie amyloid
plaques, and neurofibrillary tangles, and AD-associated cognitive impairment, has long …

Age‐related central neurodegenerative diseases, such as Alzheimer's and Parkinson's
disease, are a rising public health concern and have been plagued by repeated drug …

Amyloid-β (Aβ) accumulation is a pathological hallmark of Alzheimer's disease (AD). The
receptor for advanced glycation end products (RAGE) is involved in the production and …

The circadian clock is synchronized to the 24 h day by environmental light which is
transmitted from the retina to the suprachiasmatic nucleus (SCN) primarily via the …

The neurotransmitter γ-aminobutyric acid (GABA) is involved in the process of memory. It
has been reported that the inhibition of GABA B receptors has beneficial effects on cognition …

Abstract Background Cholinergic hypothesis of Alzheimer's disease (AD) is based on the
findings that a reduced and/or perturbed cholinergic activity in the central nervous system …

Abstract Background: Alzheimer Disease (AD) is the most common cause of dementia and it
involves a high social and economic cost worldwide, and the health system still does not …

Eye disease is one of the primary medical conditions that requires attention and therapeutic
intervention in ageing populations worldwide. Further, the global burden of diabetes and …

Our work explores the relationship between G protein-coupled receptor kinase-5 (GRK5)
single nucleotide polymorphisms and Alzheimer's disease risk. We confirmed that GRK5 …