Dendrimer: An update on recent developments and future opportunities for the brain tumors diagnosis and treatment

M Kaurav, S Ruhi, HA Al-Goshae, AK Jeppu… - Frontiers in …, 2023 - frontiersin.org
A brain tumor is an uncontrolled cell proliferation, a mass of tissue composed of cells that
grow and divide abnormally and appear to be uncontrollable by the processes that normally …

Phosphorous dendron micelles as a nanomedicine platform for cooperative tumor chemoimmunotherapy via synergistic modulation of immune cells

M Zhan, J Qiu, Y Fan, L Chen, Y Guo… - Advanced …, 2023 - Wiley Online Library
Abstract Design of effective nanomedicines to modulate multiple immune cells to overcome
the immune‐suppressive tumor microenvironment is desirable to improve the overall poor …

Supramolecular Self‐Associations of Amphiphilic Dendrons and Their Properties

E Apartsin, AM Caminade - Chemistry–A European Journal, 2021 - Wiley Online Library
This review presents precisely defined amphiphilic dendrons, their self‐association
properties, and their different uses. Dendrons, also named dendritic wedges, are composed …

[HTML][HTML] Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury

J Li, L Chen, C Li, Y Fan, M Zhan, H Sun, S Mignani… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Development of novel nanomedicines to inhibit pro-inflammatory cytokine
expression and reactive oxygen species (ROS) generation for anti-inflammatory therapy of …

Engineered stable bioactive per se amphiphilic phosphorus dendron nanomicelles as a highly efficient drug delivery system to take down breast cancer in vivo

L Chen, L Cao, M Zhan, J Li, D Wang… - …, 2022 - ACS Publications
Conventional small molecular chemical drugs always have challenging limitations in cancer
therapy due to their high systemic toxicity and low therapeutic efficacy. Nanotechnology has …

Phosphorus core–shell tecto dendrimers for enhanced tumor imaging: the rigidity of the backbone matters

M Zhan, D Wang, L Zhao, L Chen, Z Ouyang… - Biomaterials …, 2023 - pubs.rsc.org
Nanoplatforms with amplified passive tumor targeting and enhanced protein resistance can
evade unnecessary uptake by the reticuloendothelial system and achieve high tumor …

Diselenide-crosslinked nanogels laden with gold nanoparticles and methotrexate for immunomodulation-enhanced chemotherapy and computed tomography …

B Jia, Y Gao, Z Ouyang, S Shen, M Shen… - Journal of Materials …, 2023 - pubs.rsc.org
It remains an extreme challenge to develop multifunctional drug delivery systems with tumor
specificity and a tumor microenvironment (TME) remodeling ability for achieving improved …

Unsymmetrical Low-Generation Cationic Phosphorus Dendrimers as a Nonviral Vector to Deliver MicroRNA for Breast Cancer Therapy

Y Zou, S Shen, A Karpus, H Sun, R Laurent… - …, 2024 - ACS Publications
The development of nonviral dendritic polymers with a simple molecular backbone and
great gene delivery efficiency to effectively tackle cancer remains a great challenge …

AB5 Derivatives of Cyclotriphosphazene for the Synthesis of Dendrons and Their Applications

A Zibarov, A Oukhrib, J Aujard Catot, CO Turrin… - Molecules, 2021 - mdpi.com
AB5 compounds issued from the reactivity of hexachlorocyclotriphosphazene are relatively
easy to obtain using two ways: either first the reaction of one chloride with one reagent …

Impact of molecular rigidity on the gene delivery efficiency of core–shell tecto dendrimers

D Wang, L Chen, Y Gao, C Song, Z Ouyang… - Journal of Materials …, 2021 - pubs.rsc.org
We report the construction of two types of core–shell tecto dendrimers (CSTDs) with different
core rigidities to illustrate the impact of molecular rigidity on their gene delivery efficiency …