Pathophysiology of RAGE in inflammatory diseases
H Dong, Y Zhang, Y Huang, H Deng - Frontiers in Immunology, 2022 - frontiersin.org
The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
S100A8 and S100A9 in Cancer
Y Chen, Y Ouyang, Z Li, X Wang, J Ma - Biochimica et Biophysica Acta …, 2023 - Elsevier
Abstract S100A8 and S100A9 are Ca 2+ binding proteins that belong to the S100 family.
Primarily expressed in neutrophils and monocytes, S100A8 and S100A9 play critical roles in …
Primarily expressed in neutrophils and monocytes, S100A8 and S100A9 play critical roles in …
Key genes associated with non-alcoholic fatty liver disease and polycystic ovary syndrome
Y Chen, L Ma, Z Ge, Y Pan, L Xie - Frontiers in molecular biosciences, 2022 - frontiersin.org
Background: Polycystic ovary syndrome (PCOS) is the most common metabolic and
endocrinopathies disorder in women of reproductive age and non-alcoholic fatty liver …
endocrinopathies disorder in women of reproductive age and non-alcoholic fatty liver …
S100A12 in digestive diseases and health: a scoping review
A Carvalho, J Lu, JD Francis, RE Moore… - Gastroenterology …, 2020 - Wiley Online Library
Calgranulin proteins are an important class of molecules involved in innate immunity. These
members of the S100 class of the EF‐hand family of calcium‐binding proteins have …
members of the S100 class of the EF‐hand family of calcium‐binding proteins have …
Lysozyme as the anti-proliferative agent to block the interaction between S100A6 and the RAGE V domain
In this report, using NMR and molecular modeling, we have studied the structure of
lysozyme-S100A6 complex and the influence of tranilast [N-(3, 4-dimethoxycinnamoyl) …
lysozyme-S100A6 complex and the influence of tranilast [N-(3, 4-dimethoxycinnamoyl) …
Development of predictive models for identifying potential S100A9 inhibitors based on machine learning methods
S100A9 is a potential therapeutic target for various disease including prostate cancer,
colorectal cancer, and Alzheimer's disease. However, the sparsity of atomic level data, such …
colorectal cancer, and Alzheimer's disease. However, the sparsity of atomic level data, such …
Interactions between s100a9 and alpha-synuclein: insight from NMR spectroscopy
S100A9 is a pro-inflammatory protein that co-aggregates with other proteins in amyloid fibril
plaques. S100A9 can influence the aggregation kinetics and amyloid fibril structure of alpha …
plaques. S100A9 can influence the aggregation kinetics and amyloid fibril structure of alpha …
Differential expression and role of S100 proteins in chronic rhinosinusitis
JS Sumsion, A Pulsipher, JA Alt - Current opinion in allergy and …, 2020 - journals.lww.com
The reported differential expression patterns and activities of psoriasin and calgranulins
suggest that S100 proteins exert unique and concerted roles in mediating immunity in …
suggest that S100 proteins exert unique and concerted roles in mediating immunity in …
Discerning the promising binding sites of S100/calgranulins and their therapeutic potential in atherosclerosis
Introduction Atherosclerosis is a chronic inflammatory disease in which the members of
S100 family proteins (calgranulins) bind with their receptors, particularly receptor for …
S100 family proteins (calgranulins) bind with their receptors, particularly receptor for …
Virtual Probing on the Influence of Ca2+ and Zn2+ Bound S100A8 and S100A9 Proteins Towards their Interaction Against Pattern Recognition Receptors Aggravating …
Danger-associated molecular patterns (DAMPs) are released on the onset of tissue injury or
death, which tend to trigger innate immunity and regulate various immune pathways. Among …
death, which tend to trigger innate immunity and regulate various immune pathways. Among …