Long non-coding RNAs and nuclear factor-κB crosstalk in cancer and other human diseases

SC Gupta, N Awasthee, V Rai, S Chava… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The regulation of the pleiotropic transcription factor, nuclear factor-κB (NF-κB) by miRNAs
and proteins is extensively studied. More recently, the NF-κB signaling was also reported to …

The Drosophila toll pathway in innate immunity: from the core pathway toward effector functions

S Valanne, L Vesala, MK Maasdorp… - The Journal of …, 2022 - journals.aai.org
The fruit fly Drosophila melanogaster Toll signaling pathway has an evolutionarily
conserved role in controlling immune responses. Whereas the microbial recognition …

Translation and natural selection of micropeptides from long non-canonical RNAs

P Patraquim, EG Magny, JI Pueyo, AI Platero… - Nature …, 2022 - nature.com
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but lacking
canonical coding sequences. Apparently unable to produce peptides, lncRNA function …

Insect-pathogen crosstalk and the cellular-molecular mechanisms of insect immunity: uncovering the underlying signaling pathways and immune regulatory function of …

DK Mahanta, TK Bhoi, J Komal, I Samal… - Frontiers in …, 2023 - frontiersin.org
Multicellular organisms are constantly subjected to pathogens that might be harmful.
Although insects lack an adaptive immune system, they possess highly effective anti …

The Aedes aegypti siRNA pathway mediates broad-spectrum defense against human pathogenic viruses and modulates antibacterial and antifungal defenses

Y Dong, S Dong, NB Dizaji, N Rutkowski… - PLoS …, 2022 - journals.plos.org
The mosquito's innate immune system defends against a variety of pathogens, and the
conserved siRNA pathway plays a central role in the control of viral infections. Here, we …

Advances in the immune regulatory role of non-coding RNAs (miRNAs and lncRNAs) in insect-pathogen interactions

UAE Moure, T Tan, L Sha, X Lu, Z Shao… - Frontiers in …, 2022 - frontiersin.org
Insects are by far the most abundant and diverse living organisms on earth and are
frequently prone to microbial attacks. In other to counteract and overcome microbial …

Long non-coding RNAs regulate Aedes aegypti vector competence for Zika virus and reproduction

A Belavilas-Trovas, S Tastsoglou, S Dong, M Kefi… - PLoS …, 2023 - journals.plos.org
Long non-coding RNAs (lncRNAs) play critical regulatory roles in various cellular and
metabolic processes in mosquitoes and all other organisms studied thus far. In particular …

Insights into the Functions of LncRNAs in Drosophila

K Li, Y Tian, Y Yuan, X Fan, M Yang, Z He… - International journal of …, 2019 - mdpi.com
Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs longer than 200
nucleotides (nt). LncRNAs have high spatiotemporal specificity, and secondary structures …

Cellular and humoral immune interactions between Drosophila and its parasitoids

L Yang, LM Qiu, Q Fang, DW Stanley, GY Ye - Insect Science, 2021 - Wiley Online Library
The immune interactions occurring between parasitoids and their host insects, especially in
Drosophila–wasp models, have long been the research focus of insect immunology and …

Lipopolysaccharide -mediated resistance to host antimicrobial peptides and hemocyte-derived reactive-oxygen species are the major Providencia alcalifaciens virulence factors …

M Shaka, A Arias-Rojas, A Hrdina, D Frahm… - PLoS …, 2022 - journals.plos.org
Bacteria from the genus Providencia are ubiquitous Gram-negative opportunistic pathogens,
causing “travelers' diarrhea”, urinary tract, and other nosocomial infections in humans. Some …