Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment

Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

Effect of exosomal miRNA on cancer biology and clinical applications

Z Sun, K Shi, S Yang, J Liu, Q Zhou, G Wang, J Song… - Molecular cancer, 2018 - Springer
Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …

[HTML][HTML] Therapeutic potential of targeting the Wnt/β-catenin signaling pathway in colorectal cancer

X Cheng, X Xu, D Chen, F Zhao, W Wang - Biomedicine & …, 2019 - Elsevier
Aberrant Wnt/β-catenin signaling has often been reported in different cancers, particularly
colorectal cancer (CRC), and this signaling cascade is central to carcinogenesis …

Recent advancements of coumarin-based anticancer agents: An up-to-date review

T Al-Warhi, A Sabt, EB Elkaeed, WM Eldehna - Bioorganic Chemistry, 2020 - Elsevier
Heading the list of the critical health-related issues worldwide, cancer continues to be a one
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …

Ageing, cellular senescence and neurodegenerative disease

M Kritsilis, S V. Rizou, PN Koutsoudaki… - International journal of …, 2018 - mdpi.com
Ageing is a major risk factor for developing many neurodegenerative diseases. Cellular
senescence is a homeostatic biological process that has a key role in driving ageing. There …

Anticancer activity of propolis and its compounds

E Forma, M Bryś - Nutrients, 2021 - mdpi.com
Propolis is a natural material that honey bees (Apis mellifera) produce from various
botanical sources. The therapeutic activity of propolis, including antibacterial, antifungal, and …

Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review

RY Gan, HB Li, ZQ Sui, H Corke - Critical reviews in food science …, 2018 - Taylor & Francis
Green tea is one of the most popular beverages in the world, especially in Asian countries.
Consumption of green tea has been demonstrated to possess many health benefits, which …

Signal transduction pathways in breast cancer: the important role of PI3K/Akt/mTOR

MA Ortega, O Fraile-Martínez, Á Asúnsolo… - Journal of …, 2020 - Wiley Online Library
Breast cancer is the cancer with the highest prevalence in women and is the number‐one
cause of cancer mortality worldwide. Cell transduction is a fundamental process in the …

Oxidative metabolism drives immortalization of neural stem cells during tumorigenesis

F Bonnay, A Veloso, V Steinmann, T Köcher… - Cell, 2020 - cell.com
Metabolic reprogramming is a key feature of many cancers, but how and when it contributes
to tumorigenesis remains unclear. Here we demonstrate that metabolic reprogramming …