Noncoding RNAs in age-related cardiovascular diseases
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
adult population worldwide and represent a severe economic burden and public health …
adult population worldwide and represent a severe economic burden and public health …
microRNA in cardiovascular aging and age-related cardiovascular diseases
C de Lucia, K Komici, G Borghetti… - Frontiers in …, 2017 - frontiersin.org
Over the last decades, life expectancy has significantly increased although several chronic
diseases persist in the population, with aging as the leading risk factor. Despite …
diseases persist in the population, with aging as the leading risk factor. Despite …
MiR-125a promotes paclitaxel sensitivity in cervical cancer through altering STAT3 expression
Z Fan, H Cui, H Yu, Q Ji, L Kang, B Han, J Wang… - Oncogenesis, 2016 - nature.com
Cervical cancer (CC) is one of the most common malignancies in women. Paclitaxel is the
front-line chemotherapeutic agent for treating CC. However, its therapeutic efficacy is limited …
front-line chemotherapeutic agent for treating CC. However, its therapeutic efficacy is limited …
[HTML][HTML] miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss
Postmenopausal osteoporosis (PMOP) is a severe health issue faced by postmenopausal
women. microRNA-128 (miR-128) is associated with aging, inflammatory signaling, and …
women. microRNA-128 (miR-128) is associated with aging, inflammatory signaling, and …
MicroRNAs in cardiovascular ageing
MicroRNAs (miRs) have emerged as potent regulators of pathways in physiological and
disease contexts. This review focuses on the role of miRs in ageing of the cardiovascular …
disease contexts. This review focuses on the role of miRs in ageing of the cardiovascular …
The emerging role of miR‐128 in musculoskeletal diseases
Abstract MicroRNA‐128 (miR‐128) is associated with cell proliferation, differentiation,
migration, apoptosis, and survival. Genetic analysis studies have demonstrated that miR …
migration, apoptosis, and survival. Genetic analysis studies have demonstrated that miR …
miR‐125a‐5p increases cellular DNA damage of aging males and perturbs stage‐specific embryo development via Rbm38‐p53 signaling
K Liang, L Yao, S Wang, L Zheng, Z Qian, Y Ge… - Aging …, 2021 - Wiley Online Library
An increasing number of men are fathering children at an older age than in the past. While
advanced maternal age has long been recognized as a risk factor for adverse reproductive …
advanced maternal age has long been recognized as a risk factor for adverse reproductive …
Sexual dimorphism in the fetal cardiac response to maternal nutrient restriction
S Muralimanoharan, C Li, ES Nakayasu… - Journal of molecular and …, 2017 - Elsevier
Poor maternal nutrition causes intrauterine growth restriction (IUGR); however, its effects on
fetal cardiac development are unclear. We have developed a baboon model of moderate …
fetal cardiac development are unclear. We have developed a baboon model of moderate …
Comprehensive transcriptional landscape of porcine cardiac and skeletal muscles reveals differences of aging
J Chen, Q Zou, D Lv, Y Wei, MA Raza, Y Chen… - …, 2017 - pmc.ncbi.nlm.nih.gov
Aging significantly affects the cardiac muscle (CM) and skeletal muscles (SM). Since the
aging process of CM and SM may be different, high throughput RNA sequencing was …
aging process of CM and SM may be different, high throughput RNA sequencing was …
CHRONOS: a time-varying method for microRNA-mediated subpathway enrichment analysis
Motivation: In the era of network medicine and the rapid growth of paired time series
mRNA/microRNA expression experiments, there is an urgent need for pathway enrichment …
mRNA/microRNA expression experiments, there is an urgent need for pathway enrichment …