The multifaceted roles of breast milk antibodies

C Atyeo, G Alter - Cell, 2021 - cell.com
Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …

Maternal vaccination: a review of current evidence and recommendations

M Etti, A Calvert, E Galiza, S Lim, A Khalil… - American Journal of …, 2022 - Elsevier
Maternal vaccination is an effective means of protecting pregnant women, their fetuses, and
infants from vaccine-preventable infections. Despite the availability of sufficient safety data to …

Association of human milk antibody induction, persistence, and neutralizing capacity with SARS-CoV-2 infection vs mRNA vaccination

BE Young, AE Seppo, N Diaz, C Rosen-Carole… - JAMA …, 2022 - jamanetwork.com
Importance Long-term effect of parental COVID-19 infection vs vaccination on human milk
antibody composition and functional activity remains unclear. Objective To compare …

COVID-19 mRNA vaccines drive differential antibody Fc-functional profiles in pregnant, lactating, and nonpregnant women

C Atyeo, EA DeRiso, C Davis, EA Bordt… - Science translational …, 2021 - science.org
Substantial immunological changes occur throughout pregnancy to render the mother
immunologically tolerant to the fetus and allow fetal growth. However, additional local and …

Vertically transferred immunity in neonates: mothers, mechanisms and mediators

M Albrecht, PC Arck - Frontiers in Immunology, 2020 - frontiersin.org
Over the last years, an increasing number of outbreaks of vaccine-preventable infectious
diseases has been reported. Besides elderly and immunocompromised individuals …

SARS-CoV-2 antibodies in breast milk after vaccination

DS Romero Ramírez, MM Lara Pérez… - …, 2021 - publications.aap.org
METHODS We conducted a prospective cohort single-institution study from February 2 to
April 4, 2021. Women who reported to be breastfeeding at the time of their coronavirus …

Codominant IgG and IgA expression with minimal vaccine mRNA in milk of BNT162b2 vaccinees

JM Low, Y Gu, MSF Ng, Z Amin, LY Lee, YPM Ng… - npj Vaccines, 2021 - nature.com
Lactating women can produce protective antibodies in their milk after vaccination, which has
informed antenatal vaccination programs for diseases such as influenza and pertussis …

IgA antibodies and IgA deficiency in SARS-CoV-2 infection

I Quinti, EP Mortari, A Fernandez Salinas… - Frontiers in Cellular …, 2021 - frontiersin.org
A large repertoire of IgA is produced by B lymphocytes with T-independent and T-dependent
mechanisms useful in defense against pathogenic microorganisms and to reduce immune …

COVID-19 mRNA vaccine and antibody response in lactating women: a prospective cohort study

N Charepe, J Gonçalves, AM Juliano, DG Lopes… - BMC pregnancy and …, 2021 - Springer
Background Immunological protection via breastfeeding is well known. The immunological
profile of human milk changes during lactation. No clinical trials have been conducted in …

Maternal immunisation: collaborating with mother nature

A Marchant, M Sadarangani, M Garand… - The lancet infectious …, 2017 - thelancet.com
Maternal immunisation has the potential to substantially reduce morbidity and mortality from
infectious diseases after birth. The success of tetanus, influenza, and pertussis immunisation …