Global environmental and toxicological data of emerging plasticizers: current knowledge, regrettable substitution dilemma, green solution and future perspectives

A Qadeer, M Anis, GR Warner, C Potts… - Green …, 2024 - pubs.rsc.org
The global plasticizer market is projected to increase from $17 billion in 2022 to $22.5 billion
in 2027. Various emerging/alternative plasticizers entered the market following the ban on …

Neonatal exposure to phthalates and their alternatives and associated thyroid disorders: Levels, potential health risks, and mechanisms

Y Chen, X Weng, Y Hu, J Yin, S Liu, Q Zhu, L Hu… - Journal of …, 2024 - Elsevier
The number of newborns born with diseases is increasing recently. Thyroid hormones (THs)
are closely related to the growth and development of the newborn in the mother's womb and …

Impact of acetyl tributyl citrate on gonadal sex differentiation and expression of biomarker genes for endocrine disruption in Japanese medaka

Y Horie, M Nomura, UDL Ernesto, A Naija, P Akkajit… - Aquatic Toxicology, 2023 - Elsevier
Plasticizers are broadly classified as phthalate or nonphthalate. Recently, acetyl tributyl
citrate (ATBC), an environmentally friendly nonphthalate plasticizer, was revealed to have …

Exploring the underlying molecular mechanism of tri (1, 3-dichloropropyl) phosphate-induced neurodevelopmental toxicity via thyroid hormone disruption in zebrafish …

Y Xu, L Yang, Y Teng, J Li, N Li - Aquatic Toxicology, 2023 - Elsevier
Abstract Tri (1, 3-dichloropropyl) phosphate (TDCPP) is widespread in the environment as a
typical thyroid hormone-disrupting chemical. Here, we aimed to explore the toxicological …

Food chain-mediated variation in excretion times of microplastics: Unraveling the interactions with plasticizers

Y Horie, U Dorcas, K Mitsunaga, P Akkajit… - Regional Studies in …, 2024 - Elsevier
Microplastics are global environmental pollutants. Further, there has been growing concern
regarding the contamination of plasticizers. In this study, we first found that Daphnia magna …

Effect of diisobutyl adipate on the expression of biomarker genes that respond to endocrine disruption and on gonadal sexual differentiation in Japanese medaka …

Y Horie, Y Chihaya, CK Yap, JM Ríos… - … and Physiology Part C …, 2024 - Elsevier
Phthalate and non-phthalate plasticizers are used in polymer materials, such as plastic and
rubber. It has recently been found that diisobutyl adipate (DIBA), which is considered an …

Occurrence and ecological risk assessment of 16 plasticizers in the rivers and estuaries in Japan

D Uaciquete, A Sawada, T Chiba, EM Pythias, T Iguchi… - Chemosphere, 2024 - Elsevier
Owing to growing concerns about the adverse effects of phthalate plasticizers, non-phthalate
plasticizers are being increasingly used as their replacement. However, information on the …

Exploring DiPP (Diisopentyl Phthalate) Neurotoxicity and the Detoxification Process in Zebrafish Larvae–A Silent Contaminant?

BA Leite, B Rossato, DJ Dorta, C Gravato… - Environmental …, 2025 - Elsevier
Diisopentyl phthalate (DiPP) is present in many consumer goods, but can be absorbed into
the human body, and can disrupt the endocrine system affecting reproductive health and …

Alterations in neurotransmitters, steroid hormones, vitellogenin, and antioxidant system induced by di-n-butyl phthalate and di-isopentyl phthalate on catfish Rhamdia …

IC Guiloski, T Vicari, M Vicentini, LF Oya-Silva… - … Science and Pollution …, 2024 - Springer
Phthalates, such as di-n-butyl phthalate (DBP) and di-isopentyl phthalate (DiPeP), are
pollutants with a high potential for endocrine disruption. This study aimed to evaluate …

Iopanoic acid alters thyroid hormone-related gene expression, thyroid hormone levels, swim bladder inflation, and swimming performance in Japanese medaka

Y Horie, A Sawada, U Dorcas, BR Ramaswamy… - … and Physiology Part C …, 2024 - Elsevier
Disruption of the thyroid hormone system by synthetic chemicals is gaining attention owing
to its potential negative effects on organisms. In this study, the effects of the dio-inhibitor …