[HTML][HTML] Toward a global virus genomic surveillance network
The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating
its utility for public health. Now, we must harness the momentum that led to increased …
its utility for public health. Now, we must harness the momentum that led to increased …
[HTML][HTML] Global SARS-CoV-2 genomic surveillance: What we have learned (so far)
The COVID-19 pandemic has brought significant challenges for genomic surveillance
strategies in public health systems worldwide. During the past thirty-four months, many …
strategies in public health systems worldwide. During the past thirty-four months, many …
Incorporating variant frequencies data into short-term forecasting for COVID-19 cases and deaths in the USA: a deep learning approach
Background Since the US reported its first COVID-19 case on January 21, 2020, the science
community has been applying various techniques to forecast incident cases and deaths. To …
community has been applying various techniques to forecast incident cases and deaths. To …
The genetic architecture of protein stability
AJ Faure, A Martí-Aranda, C Hidalgo-Carcedo… - Nature, 2024 - nature.com
There are more ways to synthesize a 100-amino acid (aa) protein (20100) than there are
atoms in the universe. Only a very small fraction of such a vast sequence space can ever be …
atoms in the universe. Only a very small fraction of such a vast sequence space can ever be …
Understanding the influence of host radiation on symbiont speciation through parasites of species flocks
(Adaptive) radiations have attracted evolutionary biologists for a long time as ideal model
systems to study patterns and processes of often rapid speciation. However, whereas a …
systems to study patterns and processes of often rapid speciation. However, whereas a …
Digitized Kinetic Analysis Enhances Genotyping Capacity of CRISPR-Based Biosensing
CRISPR/Cas systems have been widely employed for nucleic acid biosensing and have
been further advanced for mutation detection by virtue of the sequence specificity of crRNA …
been further advanced for mutation detection by virtue of the sequence specificity of crRNA …
Phylogenomic early warning signals for SARS-CoV-2 epidemic waves
Background Epidemic waves of coronavirus disease 2019 (COVID-19) infections have often
been associated with the emergence of novel severe acute respiratory syndrome …
been associated with the emergence of novel severe acute respiratory syndrome …
[HTML][HTML] Real-time genomic surveillance for enhanced control of infectious diseases and antimicrobial resistance
MJ Struelens, C Ludden, G Werner, V Sintchenko… - Frontiers in …, 2024 - frontiersin.org
This article advocates for mobilizing pathogen genomic surveillance to contain and mitigate
health threats from infectious diseases and antimicrobial resistance (AMR), building upon …
health threats from infectious diseases and antimicrobial resistance (AMR), building upon …
Phenotypic drug-susceptibility profiles and genetic analysis based on whole-genome sequencing of Mycobacterium avium complex isolates in Thailand
A Sirichoat, O Kaewprasert, Y Hinwan, K Faksri - Plos one, 2023 - journals.plos.org
Mycobacterium avium complex (MAC) infections are a significant clinical challenge.
Determining drug-susceptibility profiles and the genetic basis of drug resistance is crucial for …
Determining drug-susceptibility profiles and the genetic basis of drug resistance is crucial for …
Pathogen genomic surveillance status among lower resource settings in Asia
M Getchell, S Wulandari, R de Alwis… - Nature …, 2024 - nature.com
Asia remains vulnerable to new and emerging infectious diseases. Understanding how to
improve next generation sequencing (NGS) use in pathogen surveillance is an urgent …
improve next generation sequencing (NGS) use in pathogen surveillance is an urgent …