Abstract Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor
with many important functions in the biology of normal and transformed cells. Its regulation is …

Our understanding of cancer and the key pathways that drive cancer survival has expanded
rapidly over the past several decades. However, there are still important challenges that …

The proinflammatory cytokines interleukin‐1β (IL‐1β) and tumor necrosis factor‐α (TNF‐α)
are involved in the corneal inflammatory response and wound healing following corneal …

Ciliary neurotrophic factor (CNTF), a well-known neuroprotective cytokine, has been found
to play an important role in neurogenesis and functional regulations of neural stem cells. As …

The p53-related gene p63 is required for epithelial cell establishment and its expression is
often altered in tumor cells. Great strides have been made in understanding the pathways …

The p53 family member p63 exists as two major protein variants (TAp63 and ΔNp63) with
distinct expression patterns and functional properties. Whilst downstream target genes of …

Purpose: Corneal transplantation can treat corneal endothelial diseases. Implanting
cultivated human corneal endothelial cells (HCECs) via a cell carrier has clinical value as an …

To avoid xenogeneic infection, we report a novel protocol for producing animal-derived
component-free oral mucosal epithelial cells (OMECs) sheet for transplantation, in which …

Epidermis is composed mainly of keratinocytes and is the major barrier of human body. The
development and maintenance of normal epithelial structures and functions require the …

Cardiac fibrosis is a serious health problem because it is a common pathological change in
almost all forms of cardiovascular diseases. Cardiac fibrosis is characterized by the …