Vibrational spectroscopy fingerprinting in medicine: from molecular to clinical practice

V Balan, CT Mihai, FD Cojocaru, CM Uritu, G Dodi… - Materials, 2019 - mdpi.com
In the last two decades, Fourier Transform Infrared (FTIR) and Raman spectroscopies turn
out to be valuable tools, capable of providing fingerprint-type information on the composition …

[HTML][HTML] Raman spectroscopy for medical diagnostics—From in-vitro biofluid assays to in-vivo cancer detection

K Kong, C Kendall, N Stone, I Notingher - Advanced drug delivery reviews, 2015 - Elsevier
Raman spectroscopy is an optical technique based on inelastic scattering of light by
vibrating molecules and can provide chemical fingerprints of cells, tissues or biofluids. The …

Raman spectroscopy: techniques and applications in the life sciences

DW Shipp, F Sinjab, I Notingher - Advances in Optics and Photonics, 2017 - opg.optica.org
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Raman spectroscopy of blood and blood components

CG Atkins, K Buckley, MW Blades… - Applied …, 2017 - journals.sagepub.com
Blood is a bodily fluid that is vital for a number of life functions in animals. To a first
approximation, blood is a mildly alkaline aqueous fluid (plasma) in which a large number of …

Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content

ZJ Smith, C Lee, T Rojalin, RP Carney… - Journal of …, 2015 - Taylor & Francis
Current analysis of exosomes focuses primarily on bulk analysis, where exosome-to-
exosome variability cannot be assessed. In this study, we used Raman spectroscopy to …

In vivo lipidomics using single-cell Raman spectroscopy

H Wu, JV Volponi, AE Oliver… - Proceedings of the …, 2011 - National Acad Sciences
We describe a method for direct, quantitative, in vivo lipid profiling of oil-producing
microalgae using single-cell laser-trapping Raman spectroscopy. This approach is …

Developments in spontaneous and coherent Raman scattering microscopic imaging for biomedical applications

C Krafft, IW Schie, T Meyer, M Schmitt… - Chemical Society …, 2016 - pubs.rsc.org
First, the potential role of Raman-based techniques in biomedicine is introduced. Second,
an overview about the instrumentation for spontaneous and coherent Raman scattering …

Separation of distinct exosome subpopulations: isolation and characterization approaches and their associated challenges

K Singh, R Nalabotala, KM Koo, S Bose, R Nayak… - Analyst, 2021 - pubs.rsc.org
Exosomes are nano-sized extracellular vesicles that serve as a communications system
between cells and have shown tremendous promise as liquid biopsy biomarkers in …

Raman and CARS microspectroscopy of cells and tissues

C Krafft, B Dietzek, J Popp - Analyst, 2009 - pubs.rsc.org
Raman spectroscopy has been recognized to be a powerful tool to study cells and tissues
because the method provides molecular information without external markers such as stains …

Cell separation: Terminology and practical considerations

MJ Tomlinson, S Tomlinson… - Journal of tissue …, 2013 - journals.sagepub.com
Cell separation is a powerful tool in biological research. Increasing usage, particularly within
the tissue engineering and regenerative medicine communities, means that researchers …