[HTML][HTML] Artemisinin-based combination therapy (ACT) and drug resistance molecular markers: A systematic review of clinical studies from two malaria endemic …

A Arya, LPK Foko, S Chaudhry, A Sharma… - International Journal for …, 2021 - Elsevier
Artemisinin-based combination therapies (ACT) are currently used as a first-line malaria
therapy in endemic countries worldwide. This systematic review aims at presenting the …

Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Mali: a systematic review and meta-analysis

FO Maiga, M Wele, SM Toure, M Keita, CO Tangara… - Malaria Journal, 2021 - Springer
Background Artemisinin-based combination therapy (ACT) was deployed in 2005 as an
alternative to chloroquine and is considered the most efficacious treatment currently …

[HTML][HTML] New insights into the spread of resistance to artemisinin and its analogues

N Noreen, A Ullah, SM Salman, Y Mabkhot… - Journal of global …, 2021 - Elsevier
Plasmodium falciparum, the causative agent of malaria, has been developing resistance to
several drugs worldwide for more than five decades. Initially, resistance was against drugs …

Access to Artemisinin–Triazole Antimalarials via Organo-Click Reaction: High In Vitro/In Vivo Activity against Multi-Drug-Resistant Malaria Parasites

L Herrmann, M Leidenberger, HC Quadros, BW Grau… - JACS Au, 2024 - ACS Publications
Malaria is one of the most widespread diseases worldwide. Besides a growing number of
people potentially threatened by malaria, the consistent emergence of resistance against …

Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic …

MS Issa, M Warsame, MHT Mahamat, IDM Saleh… - Malaria Journal, 2023 - Springer
Abstract Background Artesunate–amodiaquine (AS–AQ) and artemether–lumefantrine (AL)
are the currently recommended first-and second-line therapies for uncomplicated …

Artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular …

VS Koko, M Warsame, B Vonhm, MK Jeuronlon… - Malaria Journal, 2022 - Springer
Background Artesunate–amodiaquine (ASAQ) and Artemether–lumefantrine (AL) are the
recommended treatment for uncomplicated Plasmodium falciparum malaria in Liberia …

Barriers to accessing malaria treatment amongst school-age children in rural Malawi

P Mhango, MP Malata, E Chipeta, A Sixpence… - Malaria Journal, 2023 - Springer
Background Over the last two decades, many countries have moved from malaria control
toward malaria elimination. However, some sub-Saharan African countries, like Malawi …

Two decades of molecular surveillance in Senegal reveal rapid changes in known drug resistance mutations over time

YD Ndiaye, W Wong, J Thwing, SF Schaffner… - Malaria Journal, 2024 - Springer
Abstract Background Drug resistance in Plasmodium falciparum is a major threat to malaria
control efforts. Pathogen genomic surveillance could be invaluable for monitoring current …

Efficacy and safety of dihydroartemisinin–piperaquine versus artemether–lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Ugandan …

DG Assefa, ED Zeleke, D Bekele, HA Tesfahunei… - Malaria journal, 2021 - Springer
Background The emergence of artemisinin resistance in Southeast Asia and Plasmodium
falciparum kelch13 propeller gene mutations in sub-Saharan African pose the greatest …

Assessing the therapeutic efficacy of artemether-lumefantrine for uncomplicated malaria in Lagos, Nigeria: a comprehensive study on treatment response and …

KM Oyebola, FC Ligali, AJ Owoloye, OO Aina, YM Alo… - Malaria Journal, 2024 - Springer
Background The burden of malaria persists in sub-Saharan Africa and the emergence of
artemisinin resistance has introduced complexity to control efforts. Monitoring the efficacy of …