[HTML][HTML] Transforming Cardiotoxicity Detection in Cancer Therapies: The Promise of MicroRNAs as Precision Biomarkers

I Moscoso, M Rodríguez-Mañero… - International Journal of …, 2024 - mdpi.com
Cardiotoxicity (CDTX) is a critical side effect of many cancer therapies, leading to increased
morbidity and mortality if not addressed. Early detection of CDTX is essential, and while …

[HTML][HTML] Early detection of anthracycline-induced cardiotoxicity

W Feng, Q Wang, Y Tan, J Qiao, Q Liu, B Yang… - Clinica Chimica …, 2024 - Elsevier
Although anthracyclines are important anticancer agents, their use is limited due to various
adverse effects, particularly cardiac toxicity. Mechanisms underlying anthracycline-induced …

Cardiac miRNA expression during the development of chronic anthracycline-induced cardiomyopathy using an experimental rabbit model

M Adamcova, H Parova… - Frontiers in …, 2024 - frontiersin.org
Background: Anthracycline cardiotoxicity is a well-known complication of cancer treatment,
and miRNAs have emerged as a key driver in the pathogenesis of cardiovascular diseases …

MiRNAs and circRNAs for the diagnosis of anthracycline-induced cardiotoxicity in breast cancer patients: a narrative review

R Rosenfeld, S Riondino, V Formica, F Torino… - Journal of Personalized …, 2022 - mdpi.com
Breast cancer (BC) is the most frequent type of female cancer with increasing incidence in
recent years. Doxorubicin (DOX) is an important backbone chemotherapy in BC, responsible …

Precision Treatment of Anthracycline-Induced Cardiotoxicity: An Updated Review

Z Kuang, Y Ge, L Cao, X Wang, K Liu, J Wang… - … Treatment Options in …, 2024 - Springer
Opinion Statement Anthracycline (ANT)-induced cardiotoxicity (AIC) is a particularly
prominent form of cancer therapy-related cardiovascular toxicity leading to the limitations of …

Circulating MicroRNA as Biomarkers of Anthracycline-Induced Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review

HM Boen, M Cherubin, C Franssen, AB Gevaert… - Cardio Oncology, 2024 - jacc.org
Close monitoring for cardiotoxicity during anthracycline chemotherapy is crucial for early
diagnosis and therapy guidance. Currently, monitoring relies on cardiac imaging and serial …

MicroRNA‑96 promotes the proliferation and migration of breast cancer cells by inhibiting Smad7 expression

X Zhang, L Cong, R Yu, Q Yu, X Hou… - Oncology …, 2025 - spandidos-publications.com
The present study aimed to investigate the effects of microRNA (miR)‑96 on the proliferation
and migration of breast cancer cells, and indicated that miR‑96 may have a promoting role in …

[PDF][PDF] CARDIAC SURVEILLANCE IN ONCOLOGY: A REVIEW OF CIRCULATING BIOMARKERS AND DIAGNOSIS METHODS IN CHEMOTHERAPY-INDUCED …

E ANCA, M BANCIU, CL ROȘIORU, C DOBRE - Farmacia, 2024 - researchgate.net
Cancer survivors are at a much greater risk of developing cardiovascular diseases due to
cardiotoxic chemotherapy. Anthracyclines, antimetabolites and alkylating agents are known …

[PDF][PDF] Advances in the research on cardiotoxicity of anthracycline drugs: a comparative study of traditional Chinese medicine and Western medicine

ZY He, HC Tian, QM Li, D Tao, HW Yuan - Pharmacol Discov, 2024 - tmrjournals.com
Anthracyclines are widely used in the treatment of clinical tumors, but their cardiotoxicity has
become a significant factor limiting their use. Cardiotoxicity can lead to severe myocardial …

The response of muscle and inflammation-related miRNAs to breast cancer and its treatment

Y Jiang, H Annuk, N Miller, S Zhang, S Gupta, A Gupta - 2023 - researchsquare.com
Aim this study aims to evaluate the response of muscle-specific (miR-1, miR-133, miR-208,
miR-486, miR-499) and inflammation-related (miR-21, miR-146, and miR-155) miRNAs, well …