Chemoenzymatic methods for the synthesis of glycoproteins

C Li, LX Wang - Chemical reviews, 2018 - ACS Publications
Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

Toward automated enzymatic synthesis of oligosaccharides

L Wen, G Edmunds, C Gibbons, J Zhang… - Chemical …, 2018 - ACS Publications
Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

Microbial hemicellulases

D Shallom, Y Shoham - Current opinion in microbiology, 2003 - Elsevier
Hemicellulases are a diverse group of enzymes that hydrolyze hemicelluloses—one of the
most abundant groups of polysaccharide in nature. These enzymes have many …

Enzymes in the synthesis of glycoconjugates

RM Schmaltz, SR Hanson, CH Wong - Chemical reviews, 2011 - ACS Publications
Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

β-Galactosidases: A great tool for synthesizing galactose-containing carbohydrates

L Lu, L Guo, K Wang, Y Liu, M Xiao - Biotechnology advances, 2020 - Elsevier
Abstract β-Galactosidases, an important class of glycosidases, naturally catalyze the
hydrolysis of β-galactosidic bonds in oligosaccharides and polysaccharides. Traditionally …

Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts

T Desmet, W Soetaert, P Bojarová… - … A European Journal, 2012 - Wiley Online Library
Glycosylation can significantly improve the physicochemical and biological properties of
small molecules like vitamins, antibiotics, flavors, and fragrances. The chemical synthesis of …

[PDF][PDF] Enzyme‐responsive polymer hydrogel particles for controlled release

PD Thornton, RJ Mart, RV Ulijn - Advanced Materials, 2007 - academia.edu
Enzymes, and specifically proteases, play essential roles in a large number of biochemical
processes. Indeed, specific proteolytic enzymes have been identified to play key roles in …

[HTML][HTML] Leloir glycosyltransferases in applied biocatalysis: A multidisciplinary approach

L Mestrom, M Przypis, D Kowalczykiewicz… - International journal of …, 2019 - mdpi.com
Enzymes are nature's catalyst of choice for the highly selective and efficient coupling of
carbohydrates. Enzymatic sugar coupling is a competitive technology for industrial …

β‐Galactosidase: From its source and applications to its recombinant form

A Movahedpour, N Ahmadi… - Biotechnology and …, 2022 - Wiley Online Library
Carbohydrate‐active enzymes are a group of important enzymes playing a critical role in the
degradation and synthesis of carbohydrates. Glycosidases can hydrolyze glycosides into …

Oligosaccharide synthesis by glycosynthases

G Perugino, A Trincone, M Rossi, M Moracci - TRENDS in Biotechnology, 2004 - cell.com
Oligosaccharide synthesis is becoming increasingly important to the pharmaceutical
industry because these biomolecules have potential application as therapeutics. Enzymatic …