Type 3 diabetes and its role implications in Alzheimer's disease

TT Nguyen, QTH Ta, TKO Nguyen… - International journal of …, 2020 - mdpi.com
The exact connection between Alzheimer's disease (AD) and type 2 diabetes is still in
debate. However, poorly controlled blood sugar may increase the risk of developing …

Information retrieval and text mining technologies for chemistry

M Krallinger, O Rabal, A Lourenco, J Oyarzabal… - Chemical …, 2017 - ACS Publications
Efficient access to chemical information contained in scientific literature, patents, technical
reports, or the web is a pressing need shared by researchers and patent attorneys from …

The CHEMDNER corpus of chemicals and drugs and its annotation principles

M Krallinger, O Rabal, F Leitner, M Vazquez… - Journal of …, 2015 - Springer
The automatic extraction of chemical information from text requires the recognition of
chemical entity mentions as one of its key steps. When developing supervised named entity …

PubMed and beyond: a survey of web tools for searching biomedical literature

Z Lu - Database, 2011 - academic.oup.com
The past decade has witnessed the modern advances of high-throughput technology and
rapid growth of research capacity in producing large-scale biological data, both of which …

CHEMDNER: The drugs and chemical names extraction challenge

M Krallinger, F Leitner, O Rabal, M Vazquez… - Journal of …, 2015 - Springer
Natural language processing (NLP) and text mining technologies for the chemical domain
(ChemNLP or chemical text mining) are key to improve the access and integration of …

Application of text mining in the biomedical domain

WWM Fleuren, W Alkema - Methods, 2015 - Elsevier
In recent years the amount of experimental data that is produced in biomedical research and
the number of papers that are being published in this field have grown rapidly. In order to …

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains

C Haenig, N Atias, AK Taylor, A Mazza, MH Schaefer… - Cell reports, 2020 - cell.com
Interactome maps are valuable resources to elucidate protein function and disease
mechanisms. Here, we report on an interactome map that focuses on neurodegenerative …

Bacterial reference genes for gene expression studies by RT-qPCR: survey and analysis

DJP Rocha, CS Santos, LGC Pacheco - Antonie Van Leeuwenhoek, 2015 - Springer
The appropriate choice of reference genes is essential for accurate normalization of gene
expression data obtained by the method of reverse transcription quantitative real-time PCR …

SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets

J Guo, H Liu, J Zheng - Nucleic acids research, 2016 - academic.oup.com
Synthetic lethality (SL) is a type of genetic interaction between two genes such that
simultaneous perturbations of the two genes result in cell death or a dramatic decrease of …

Event extraction for systems biology by text mining the literature

S Ananiadou, S Pyysalo, J Tsujii, DB Kell - Trends in biotechnology, 2010 - cell.com
Systems biology recognizes in particular the importance of interactions between biological
components and the consequences of these interactions. Such interactions and their …