The use of Xenopus oocytes in electrophysiological and biophysical research constitutes a
long and successful story, providing major advances to the knowledge of the function and …

Despite huge improvements in neurobiological approaches for investigating the functional
properties of neurotransmitter receptors and ion channels, many difficulties are still …

Fritillaria bulbs are used in Traditional Chinese Medicine to treat several illnesses. Peimine
(Pm), an anti-inflammatory compound from Fritillaria, is known to inhibit some voltage …

Nicotinic acetylcholine receptors (nAChRs) are expressed in excitable and non-excitable
cells of the organism. Extensive studies suggest that nAChR ligands have therapeutic …

Integral membrane proteins represent a substantial portion of regulatory molecules in
cellular biology. Voltage-gated ion channels are a fundamental class of membrane proteins …

This study compares the lipid composition, including individual phospholipid molecular
species of solubilized nAChR detergent complexes (nAChR-DCs) with those of the bulk …

This work was aimed to determine if 1, 5-bis (4-allyldimethylammoniumphenyl) pentan-3-
one dibromide (BW284c51), the most selective acetylcholinesterase inhibitor (AchEI), affects …

Biological membranes have long been identified as key elements in a wide variety of
cellular processes including cell defense communication, photosynthesis, signal …

Voltage-gated potassium channels are often assembled with accessory proteins which
increases their functional diversity. KCNE proteins are small accessory proteins that …

In our previous study we examined the functionality and stability of nicotinic acetylcholine
receptor (nAChR)-detergent complexes (nAChR-DCs) from affinity-purified Torpedo …