SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …

Calmodulin (CaM) is recognized as a major calcium sensor and orchestrator of regulatory
events through its interaction with a diverse group of cellular proteins. Many investigations …

Cell proliferation is orchestrated through diverse proteins related to calcium (Ca 2+)
signaling inside the cell. Cellular Ca 2+ influx that occurs first by various mechanisms at the …

Many hormones, growth factors, and cytokines regulate proliferation of their target cells.
Perhaps the most universal signaling cascades required for proliferative responses are …

Calmodulin CaM is a ubiquitous Ca2+ sensor protein (16 to 18 kD) with no catalytic activity
that can, upon binding Ca2+, activate target proteins involved in various cellular processes …

▪ Abstract Calmodulin is a small Ca2+-binding protein that acts to transduce second
messenger signals into a wide array of cellular responses. Plant calmodulins share many …

Calcium (Ca2+) signaling is thought to orchestrate responses to cellular stimuli. The efficacy
of Ca2+ signaling requires mediation by Ca2+‐binding proteins.• The determination of the …

The actin cytoskeleton provides the structural basis for cell polarity in Saccharomyces
cerevisiae as well as most other eukaryotes. In Part I of this two-part commentary, presented …

Acute modulation of P/Q-type (α1A) calcium channels by neuronal activity-dependent
changes in intracellular Ca2+ concentration may contribute to short-term synaptic plasticity …

▪ Abstract A surprising variety of ion channels found in a wide range of species from Homo to
Paramecium use calmodulin (CaM) as their constitutive or dissociable Ca2+-sensing …