Naringenin nano-delivery systems and their therapeutic applications

M Bhia, M Motallebi, B Abadi, A Zarepour… - Pharmaceutics, 2021 - mdpi.com
Naringenin (NRG) is a polyphenolic phytochemical belonging to the class of flavanones and
is widely distributed in citrus fruits and some other fruits such as bergamot, tomatoes, cocoa …

Solid dispersions, part I: recent evolutions and future opportunities in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

DN Bikiaris - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: In recent years, the number of active pharmaceutical ingredients with high
therapeutic impact, but very low water solubility, has increased significantly. Thus, a great …

Therapeutic potential of naringin in neurological disorders

S Ahmed, H Khan, M Aschner, MM Hasan… - Food and Chemical …, 2019 - Elsevier
Neurological illnesses are multifactorial incurable debilitating disorders that may cause
neurodegeneration. These diseases influence approximately 30 million people around the …

Pharmacological properties and therapeutic potential of naringenin: a citrus flavonoid of pharmaceutical promise

N Rani, S Bharti, B Krishnamurthy… - Current …, 2016 - ingentaconnect.com
Naringenin chemically known as 5, 7-dihydroxy-2-(4-hydroxyphenyl) chroman-4-one is a
common dietary polyphenolic constituent of the citrus fruits. It has received considerable …

Re-appraising the potential of naringin for natural, novel orthopedic biotherapies

KE Yu, KD Alder, MT Morris… - Therapeutic …, 2020 - journals.sagepub.com
Naringin is a naturally occurring flavonoid found in plants of the Citrus genus that has
historically been used in traditional Chinese medical regimens for the treatment of …

Therapeutic potentials of crocin in medication of neurological disorders

S Ahmed, MM Hasan, M Heydari, A Rauf… - Food and Chemical …, 2020 - Elsevier
Neurological sicknesses are serious, multifactorial, debilitating disorders that may cause
neurodegeneration. Neuroprotection is the protection of the structure and capacity of …

Enhanced dissolution and bioavailability of grapefruit flavonoid Naringenin by solid dispersion utilizing fourth generation carrier

AW Khan, S Kotta, SH Ansari… - Drug development and …, 2015 - Taylor & Francis
Abstract Context: Naringenin (NRG), the aglycone flavonoid present in grapefruits,
possesses anti-inflammatory, anti-carcinogenic, anti-lipid peroxidation and hepato …

[HTML][HTML] Naringin: A potential natural product in the field of biomedical applications

A Sharma, P Bhardwaj, SK Arya - Carbohydrate Polymer Technologies and …, 2021 - Elsevier
Over the decades, the exploitation of medicinal plants has been done by numerous
merchandise companies or dealers through various conventional healers in a way to lessen …

The systems of naringenin with solubilizers expand its capability to prevent neurodegenerative diseases

A Stasiłowicz-Krzemień, M Gołębiewski… - International Journal of …, 2022 - mdpi.com
Background: Naringenin (NAR) is a flavonoid with excellent antioxidant and neuroprotective
potential that is limited by its low solubility. Thus, solid dispersions with β-cyclodextrin (β …

Methods to improve the solubility of therapeutical natural products: a review

H Jain, N Chella - Environmental Chemistry Letters, 2021 - Springer
Many natural substances are efficient in vitro and in vivo for the treatment of various
disorders. However, treatment is often limited by their low bioavailability, water solubility and …