Neocortical circuits in pain and pain relief

LL Tan, R Kuner - Nature Reviews Neuroscience, 2021 - nature.com
The sensory, associative and limbic neocortical structures play a critical role in shaping
incoming noxious inputs to generate variable pain perceptions. Technological advances in …

[HTML][HTML] Brain (re) organisation following amputation: Implications for phantom limb pain

TR Makin, H Flor - Neuroimage, 2020 - Elsevier
Following arm amputation the region that represented the missing hand in primary
somatosensory cortex (S1) becomes deprived of its primary input, resulting in changed …

The prevalence and risk factors for phantom limb pain in people with amputations: a systematic review and meta-analysis

K Limakatso, GJ Bedwell, VJ Madden, R Parker - PloS one, 2020 - journals.plos.org
Background Phantom limb pain (PLP)—pain felt in the amputated limb–is often
accompanied by significant suffering. Estimates of the burden of PLP have provided …

A virtual reality intervention for the treatment of phantom limb pain: development and feasibility results

T Rutledge, D Velez, C Depp, JR McQuaid… - Pain …, 2019 - academic.oup.com
Objective To describe the development of a virtual reality (VR) treatment for phantom limb
pain (PLP) and phantom sensations and provide feasibility data from testing the treatment in …

Effect of mirror therapy in the treatment of phantom limb pain in amputees: A systematic review of randomized placebo‐controlled trials does not find any evidence of …

M Guémann, E Olié, L Raquin, P Courtet… - European journal of …, 2023 - Wiley Online Library
Abstract Background and Objective Phantom limb pain (PLP) concerns> 50% of amputees
and has a negative impact on their rehabilitation, mental health and quality of life. Mirror …

[HTML][HTML] Reassessing referral of touch following peripheral deafferentation: The role of contextual bias

E Amoruso, DB Terhune, M Kromm, S Kirker, D Muret… - cortex, 2023 - Elsevier
Some amputees have been famously reported to perceive facial touch as arising from their
phantom hand. These referred sensations have since been replicated across multiple …

Treatment recommendations for phantom limb pain in people with amputations: an expert consensus Delphi study

K Limakatso, R Parker - PM&R, 2021 - Wiley Online Library
Background Phantom limb pain (PLP) is common and often accompanied by serious
suffering. Current systematic‐review evidence suggests that recommended treatments are …

Sensory stimulation enhances phantom limb perception and movement decoding

LE Osborn, K Ding, MA Hays, R Bose… - Journal of neural …, 2020 - iopscience.iop.org
Objective. A major challenge for controlling a prosthetic arm is communication between the
device and the user's phantom limb. We show the ability to enhance phantom limb …

Assessment of cortical reorganization and preserved function in phantom limb pain: a methodological perspective

J Andoh, C Milde, M Diers, R Bekrater-Bodmann… - Scientific reports, 2020 - nature.com
Phantom limb pain (PLP) has been associated with reorganization in primary
somatosensory cortex (S1) and preserved S1 function. Here we examined if methodological …

[HTML][HTML] The prevalence and characteristics of phantom limb pain and Non-Painful phantom phenomena in a nationwide survey of 3,374 unilateral limb amputees

M Diers, B Krumm, X Fuchs, R Bekrater-Bodmann… - The journal of pain, 2022 - Elsevier
The experience of phantom limb pain (PLP) is a common consequence of limb amputation,
resulting in severe impairments of the affected person. Previous studies have shown that …