Living materials, which are made either of or by living cells, or are synthetic materials with
programmable elements catered to cells, are environmentally responsive and can self …

The extracellular matrix (ECM) is a highly complex structure through which biochemical and
mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a …

Multiscale computational modeling aims to connect the complex networks of effects at
different length and/or time scales. For example, these networks often include intracellular …

To examine the hemostatic behaviors of neural activity and extracellular matrix (ECM)
molecules, this paper provides a mathematical model for ECM combined with a FitzHugh …

A major cause of cancer mortality is metastasis of cancer cells from a localized tumor to
other parts of the body. The interactions between cancer cells and the surrounding tumor …

Cancer attracts significant attention nowadays due to its rising global incidence, the
complexity of its biological mechanisms, and the challenges it presents in treatment and …

Metastasis is the pathogenic spread of cancer cells from a primary tumor to a secondary site
which happens at the late stages of cancer. It is caused by a variety of biological, chemical …

Metastasis, the leading cause of death in cancer patients, arises when cancer cells
disseminate from a primary solid tumour to distant organs. Growth and invasion of the solid …

Cells can sense mechanical properties of surrounding environments and also structurally
remodel the environments. Interactions between cells and extracellular matrix (ECM) play a …

We formulate haptotaxis models of cancer invasion wherein the infiltrating cancer cells can
occupy a spectrum of states in phenotype space, ranging from 'fully mesenchymal'to 'fully …