Systemic and adjuvant therapies for intrahepatic cholangiocarcinoma

YS Chun, M Javle - Cancer Control, 2017 - journals.sagepub.com
Intrahepatic cholangiocarcinoma represents the second most common primary liver cancer
and is increasing in incidence. Most patients are diagnosed at an advanced, nonsurgical …

Cholangiocarcinoma: Current opinion on clinical practice diagnostic and therapeutic algorithms: A review of the literature and a long-standing experience of a referral …

G Brandi, M Venturi, MA Pantaleo, G Ercolani… - Digestive and Liver …, 2016 - Elsevier
In the oncology landscape, cholangiocarcinoma is a challenging disease in terms of both
diagnosis and treatment. Besides anamnesis and clinical examination, a definitive diagnosis …

Early versus late recurrence of intrahepatic cholangiocarcinoma after resection with curative intent

XF Zhang, EW Beal, F Bagante… - Journal of British …, 2018 - academic.oup.com
Background The objective of this study was to investigate the characteristics, treatment and
prognosis of early versus late recurrence of intrahepatic cholangiocarcinoma (ICC) after …

Neoadjuvant vs. adjuvant chemotherapy for cholangiocarcinoma: a propensity score matched analysis

S Yadav, H Xie, I Bin-Riaz, P Sharma, U Durani… - European Journal of …, 2019 - Elsevier
Background Chemotherapy is frequently used in cholangiocarcinoma as an adjunct to
surgical resection, but the appropriate sequence of chemotherapy with surgery is unclear …

Prognostic value of lymphadenectomy for long-term outcomes in node-negative intrahepatic cholangiocarcinoma: a multicenter study

T Yoh, F Cauchy, B Le Roy, S Seo, K Taura, C Hobeika… - Surgery, 2019 - Elsevier
Background Lymphadenectomy ensures accurate staging for patients with intrahepatic
cholangiocarcinoma, especially for those without preoperatively suspected positive lymph …

Intrahepatic, perihilar and distal cholangiocarcinoma: management and outcomes

D Waseem, T Patel - Annals of hepatology, 2017 - medigraphic.com
Introduction and aims. Cholangiocarcinomas are a heterogeneous group of tumors that can
be classified into three clinically distinct types of cancers, intrahepatic, perihilar and distal …

Neoadjuvant chemotherapy for intrahepatic cholangiocarcinoma: a propensity score survival analysis supporting use in patients with high-risk disease

O Utuama, JB Permuth, G Dagne… - Annals of Surgical …, 2021 - Springer
Background Upfront surgery is the current standard for resectable intrahepatic
cholangiocarcinoma (ICC) despite high treatment failure with this approach. We sought to …

The prognostic role of lymphovascular invasion and lymph node metastasis in perihilar and intrahepatic cholangiocarcinoma

G Lurje, J Bednarsch, Z Czigany, I Lurje… - European journal of …, 2019 - Elsevier
Introduction Cholangiocellular carcinoma (CCA) is an aggressive malignancy with a dismal
prognosis. Among curative treatment options for CCA, radical surgical resection with …

Time to rethink upfront surgery for resectable intrahepatic cholangiocarcinoma? Implications from the neoadjuvant experience

MC Mason, NN Massarweh, CWD Tzeng… - Annals of surgical …, 2021 - Springer
Background While surgery is a mainstay of curative-intent treatment for patients with
intrahepatic cholangiocarcinoma (IHC), the role of neoadjuvant therapy (NT) has not been …

[HTML][HTML] Impact of adjuvant chemotherapy on survival in patients with intrahepatic cholangiocarcinoma: a multi-institutional analysis

BN Reames, F Bagante, A Ejaz, G Spolverato… - Hpb, 2017 - Elsevier
Background The benefit of adjuvant chemotherapy for resected intrahepatic
cholangiocarcinoma (ICC) is unclear. The aim of the current study was to investigate the …