Our understanding of the functions of motor system evolved remarkably in the last 20 years.
This is the consequence not only of an increase in the amount of data on this system but …

This review focuses on a novel rehabilitation approach known as action observation
treatment (AOT). It is now a well-accepted notion in neurophysiology that the observation of …

This article discusses recent evidence supporting the use of action observation therapy and
motor imagery practice for rehabilitation of Parkinson's disease. A main question that …

Despite their proven efficacy in treating neurological disorders, especially Parkinson's
disease, deep brain stimulation (DBS) systems could be further optimized to maximize …

Both phenotype and treatment response vary in patients with Parkinson's disease.
Anatomical and functional imaging studies suggest that individual symptoms may represent …

In Parkinson's disease (PD), the oscillatory activity recorded from the basal ganglia shows
dopamine-dependent changes. In the “off” parkinsonian motor state, there is prominent …

Background Resting-state functional magnetic resonance imaging studies examining low
frequency fluctuations (0.01–0.08 Hz) have revealed atypical whole brain functional …

Traditionally, the basal ganglia have been considered the main brain region implicated in
Parkinson's disease. This single area perspective gives a restricted clinical picture and limits …

While it is well documented that the motor system is more than a mere implementer of motor
actions, the possible applications of its cognitive side are still under-exploited, often …

Mirror neurons (MNs) are a fascinating class of cells originally discovered in the ventral
premotor cortex (PMv) and, subsequently, in the inferior parietal lobule (IPL) of the macaque …