S Weintraub, AH Wicklund… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Neuropsychological assessment has featured prominently over the past 30 years in the characterization of dementia associated with Alzheimer disease (AD). Clinical …
MW Bondi, EC Edmonds, AJ Jak… - Journal of …, 2014 - content.iospress.com
We compared two methods of diagnosing mild cognitive impairment (MCI): conventional Petersen/Winblad criteria as operationalized by the Alzheimer's Disease Neuroimaging …
Memory function often declines with age1, and is believed to deteriorate initially because of changes in synaptic function rather than loss of neurons2. Some individuals then go on to …
SA Shumaker, C Legault, SR Rapp, L Thal, RB Wallace… - Jama, 2003 - jamanetwork.com
ContextPostmenopausal women have a greater risk than men of developing Alzheimer disease, but studies of the effects of estrogen therapy on Alzheimer disease have been …
J Hort, JT O'Brien, G Gainotti, T Pirttila… - European Journal of …, 2010 - Wiley Online Library
Background and objectives: In 2008 a task force was set up to develop a revision of the European Federation of the Neurological Societies (EFNS) guideline for the diagnosis and …
ContextPhysical activity may help maintain cognitive function in older adults. ObjectiveTo examine the relation of long-term regular physical activity, including walking, to cognitive …
Functional magnetic resonance imaging (fMRI) studies have observed hyperactivity in the hippocampal region in individuals with Mild Cognitive Impairment (MCI). However, the …
JL Price, DW McKeel Jr, VD Buckles, CM Roe… - Neurobiology of …, 2009 - Elsevier
OBJECTIVE: To determine the frequency and possible cognitive effect of histological Alzheimer's disease (AD) in autopsied older nondemented individuals. DESIGN: Senile …
Objective: To examine the relation of performance on brief cognitive tests to development of clinically diagnosed Alzheimer disease (AD) dementia over the following 18 years in a …