Intranasal vaccines for SARS-CoV-2: From challenges to potential in COVID-19 management
Abstract Unlike conventional Coronavirus 2019 (COVID-19) vaccines, intranasal vaccines
display a superior advantage because the nasal mucosa is often the initial site of infection …
display a superior advantage because the nasal mucosa is often the initial site of infection …
Recent advances in exploiting carrageenans as a versatile functional material for promising biomedical applications
F Liu, G Duan, H Yang - International Journal of Biological Macromolecules, 2023 - Elsevier
Carrageenans are a group of biopolymers widely found in red seaweeds. Commercial
carrageenans have been traditionally used as emulsifiers, stabilizers, and thickening and …
carrageenans have been traditionally used as emulsifiers, stabilizers, and thickening and …
Nasal sprays for treating COVID-19: a scientific note
Clinical management of COVID-19 has been a daunting task. Due to the lack of specific
treatment, vaccines have been regarded as the first line of defence. Innate responses and …
treatment, vaccines have been regarded as the first line of defence. Innate responses and …
Antiviral activity of carrageenans and processing implications
M Álvarez-Viñas, S Souto, N Flórez-Fernández… - Marine Drugs, 2021 - mdpi.com
Carrageenan and carrageenan oligosaccharides are red seaweed sulfated carbohydrates
with well-known antiviral properties, mainly through the blocking of the viral attachment …
with well-known antiviral properties, mainly through the blocking of the viral attachment …
Engineered nasal dry powder for the encapsulation of bioactive compounds
A Baldelli, MA Boraey, H Oguzlu, A Cidem… - Drug Discovery …, 2022 - Elsevier
Highlights•Particle engineering can be used to design stable dry powder to be nasally
delivered;•Spray and spray freeze drying show the highest control over the properties of dry …
delivered;•Spray and spray freeze drying show the highest control over the properties of dry …
Viral inhibitors derived from macroalgae, microalgae, and cyanobacteria: A review of antiviral potential throughout pathogenesis
D Reynolds, M Huesemann, S Edmundson, A Sims… - Algal Research, 2021 - Elsevier
Viruses are abiotic obligate parasites utilizing complex mechanisms to hijack cellular
machinery and reproduce, causing multiple harmful effects in the process. Viruses represent …
machinery and reproduce, causing multiple harmful effects in the process. Viruses represent …
Carrageenan-containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures
D Schütz, C Conzelmann, G Fois… - … of Physiology-Lung …, 2021 - journals.physiology.org
Pharmaceutical interventions are urgently needed to prevent severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection and transmission. As SARS-CoV-2 infects …
syndrome coronavirus 2 (SARS-CoV-2) infection and transmission. As SARS-CoV-2 infects …
Nasal delivery as a strategy for the prevention and treatment of COVID-19
Introduction The upper respiratory tract is a major route of infection for COVID-19 and other
respiratory diseases. Thus, it appears logical to exploit the nose as administration site to …
respiratory diseases. Thus, it appears logical to exploit the nose as administration site to …
Therapeutic activity of fucoidan and carrageenan as marine algal polysaccharides against viruses
Marine resources are today a renewable source of various compounds that are used in
numerous industries. In recent years, considerable attention has been focused on diverse …
numerous industries. In recent years, considerable attention has been focused on diverse …
Nasally inhaled therapeutics and vaccination for COVID‐19: Developments and challenges
The nose is the initial site of viral infection, replication, and transmission in the human body.
Nasally inhaled vaccines may act as a promising alternative for COVID‐19 management in …
Nasally inhaled vaccines may act as a promising alternative for COVID‐19 management in …