Role of AMPK in autophagy

S Wang, H Li, M Yuan, H Fan, Z Cai - Frontiers in physiology, 2022 - frontiersin.org
Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor
in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved …

[HTML][HTML] An overview: the diversified role of mitochondria in cancer metabolism

Y Sun, Y Guo, X Shi, X Chen, W Feng… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Mitochondria are intracellular organelles involved in energy production, cell metabolism and
cell signaling. They are essential not only in the process of ATP synthesis, lipid metabolism …

Epigenetic modification of ferroptosis by non-coding RNAs in cancer drug resistance

H Wang, JS Fleishman, S Cheng, W Wang, F Wu… - Molecular Cancer, 2024 - Springer
The development of drug resistance remains a major challenge in cancer treatment.
Ferroptosis, a unique type of regulated cell death, plays a pivotal role in inhibiting tumour …

Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer

W He, Q Li, X Li - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Acetyl-CoA, as an important molecule, not only participates in multiple intracellular
metabolic reactions, but also affects the post-translational modification of proteins, playing a …

The strategic roles of four enzymes in the interconnection between metabolism and oncogene activation in non-small cell lung cancer: Therapeutic implications

P Icard, L Simula, L Fournel, K Leroy, A Lupo… - Drug Resistance …, 2022 - Elsevier
NSCLC is the leading cause of cancer mortality and represents a major challenge in cancer
therapy. Intrinsic and acquired anticancer drug resistance are promoted by hypoxia and HIF …

Terahertz metamaterial sensor for sensitive detection of citrate salt solutions

X Deng, Y Shen, B Liu, Z Song, X He, Q Zhang, D Ling… - Biosensors, 2022 - mdpi.com
Citrate salts (CSs), as one type of organic salts, have been widely used in the food and
pharmaceutical industries. Accurate and quantitative detection of CSs in food and medicine …

Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes

T Nemkov, D Stephenson, EJ Earley, GR Keele, A Hay… - Cell Metabolism, 2024 - cell.com
Mature red blood cells (RBCs) lack mitochondria and thus exclusively rely on glycolysis to
generate adenosine triphosphate (ATP) during aging in vivo or storage in blood banks …

Intracellular Glucose‐Depriving Polymer Micelles for Antiglycolytic Cancer Treatment

J Lee, K Kim, IC Kwon, KY Lee - Advanced Materials, 2023 - Wiley Online Library
A new anticancer strategy to exploit abnormal metabolism of cancer cells rather than to
merely control the drug release or rearrange the tumor microenvironment is reported. An …

Why may citrate sodium significantly increase the effectiveness of transarterial chemoembolization in hepatocellular carcinoma?

P Icard, L Simula, Z Wu, D Berzan, P Sogni… - Drug Resistance …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) represents the third cause of cancer death in men
worldwide, and its increasing incidence can be explained by the increasing occurrence of …

Cancer immunometabolism: advent, challenges, and perspective

Q Dang, B Li, B Jin, Z Ye, X Lou, T Wang, Y Wang… - Molecular Cancer, 2024 - Springer
For decades, great strides have been made in the field of immunometabolism. A plethora of
evidence ranging from basic mechanisms to clinical transformation has gradually embarked …