Neuroinflammation as a key driver of secondary neurodegeneration following stroke?

SM Stuckey, LK Ong, LE Collins-Praino… - International Journal of …, 2021 - mdpi.com
Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Role of interleukin-10 in acute brain injuries

JM Garcia, SA Stillings, JL Leclerc, H Phillips… - Frontiers in …, 2017 - frontiersin.org
Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to
brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged …

Role of inflammation and its mediators in acute ischemic stroke

R Jin, L Liu, S Zhang, A Nanda, G Li - Journal of cardiovascular …, 2013 - Springer
Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …

Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis

P Deb, S Sharma, KM Hassan - Pathophysiology, 2010 - Elsevier
Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

Anti-inflammatory targets for the treatment of reperfusion injury in stroke

A Mizuma, MA Yenari - Frontiers in neurology, 2017 - frontiersin.org
While the mainstay of acute stroke treatment includes revascularization via recombinant
tissue plasminogen activator or mechanical thrombectomy, only a minority of stroke patients …

The inflammatory response in stroke

Q Wang, XN Tang, MA Yenari - Journal of neuroimmunology, 2007 - Elsevier
Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

Inflammatory markers and onset of cardiovascular events: results from the Health ABC study

M Cesari, BWJH Penninx, AB Newman… - Circulation, 2003 - Am Heart Assoc
Background—Inflammation plays an important role in cardiovascular disease. The aim of
this study is to investigate the predictive value of several inflammatory markers on the …

Inflammatory responses in brain ischemia

M Kawabori, MA Yenari - Current medicinal chemistry, 2015 - ingentaconnect.com
Brain infarction causes tissue death by ischemia due to occlusion of the cerebral vessels
and recent work has shown that post stroke inflammation contributes significantly to the …

Cerebral ischemic damage in diabetes: an inflammatory perspective

V Shukla, AK Shakya, MA Perez-Pinzon… - Journal of …, 2017 - Springer
Stroke is one of the leading causes of death worldwide. A strong inflammatory response
characterized by activation and release of cytokines, chemokines, adhesion molecules, and …

Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence

DG Hackam, SS Anand - Jama, 2003 - jamanetwork.com
ContextAtherosclerotic vascular disease is an enormous public health problem. A number of
emerging risk factors for atherosclerosis have recently been proposed to help identify high …