The current treatment strategies in advanced malignancies remain limited. Notably,
immunotherapies have raised hope for a successful control of these advanced diseases, but …

Cancer immunotherapies targeting adaptive immune checkpoints have substantially
improved patient outcomes across multiple metastatic and treatment-refractory cancer types …

Micro-nano biorobots based on bacteria have demonstrated great potential for tumor
diagnosis and treatment. The bacterial gene expression and drug release should be …

Tumor-infiltrating dendritic cells (DCs) assume varied functional states that impact anti-tumor
immunity. To delineate the DC states associated with productive anti-tumor T cell immunity …

Abstract Hypoxia‐inducible factor 1 (HIF‐1) plays an indispensable role in the hypoxic tumor
microenvironment. Hypoxia and HIF‐1 are involved in multiple aspects of tumor progression …

Radiotherapy (RT) of colorectal cancer (CRC) can prime adaptive immunity against tumor-
associated antigen (TAA)–expressing CRC cells systemically. However, abscopal tumor …

Synthetic biology is driving a new era of medicine through the genetic programming of living
cells,. This transformative approach allows for the creation of engineered systems that …

Ongoing research has revealed that the existence of cancer stem cells (CSCs) is one of the
biggest obstacles in the current cancer therapy. CSCs make an influential function in tumor …

Cancer stem cells (CSCs) are self-renewing cells that facilitate tumor initiation, promote
metastasis, and enhance cancer therapy resistance. Transcriptomic analyses across many …

Enabling macrophages to phagocytose tumor cells holds great potential for cancer therapy
but suffers from tremendous challenges because the tumor cells upregulate …