Dengue vaccines: an update
JM Torres-Flores, A Reyes-Sandoval, MI Salazar - BioDrugs, 2022 - Springer
Dengue is one of the most prevalent mosquito-borne diseases in the world, affecting an
estimated 390 million people each year, according to models. For the last two decades …
estimated 390 million people each year, according to models. For the last two decades …
Current development and challenges of tetravalent live-attenuated dengue vaccines
Dengue is the most common arboviral disease caused by one of four distinct but closely
related dengue viruses (DENV) and places significant economic and public health burdens …
related dengue viruses (DENV) and places significant economic and public health burdens …
Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies
Human cytomegalovirus (HCMV) encodes multiple surface glycoprotein complexes to infect
a variety of cell types. The HCMV Pentamer, composed of gH, gL, UL128, UL130, and …
a variety of cell types. The HCMV Pentamer, composed of gH, gL, UL128, UL130, and …
Dengue virus neutralizing antibody: a review of targets, cross-reactivity, and antibody-dependent enhancement
Dengue is the most common viral infection spread by mosquitoes, prevalent in tropical
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …
Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies
Dengue virus (DENV) is a worldwide health burden, and a safe vaccine is needed.
Neutralizing antibodies bind to quaternary epitopes on DENV envelope (E) protein …
Neutralizing antibodies bind to quaternary epitopes on DENV envelope (E) protein …
Broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics
Eliciting broadly neutralizing antibodies (bNAbs) against the four dengue virus serotypes
(DENV1-4) that are spreading into new territories is an important goal of vaccine design. To …
(DENV1-4) that are spreading into new territories is an important goal of vaccine design. To …
Mammalian animal models for dengue virus infection: a recent overview
MEH Kayesh, K Tsukiyama-Kohara - Archives of virology, 2022 - Springer
Dengue, a rapidly spreading mosquito-borne human viral disease caused by dengue virus
(DENV), is a public health concern in tropical and subtropical areas due to its expanding …
(DENV), is a public health concern in tropical and subtropical areas due to its expanding …
A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial
L Li, DC Freed, Y Liu, F Li, DF Barrett, W Xiong, X Ye… - npj Vaccines, 2021 - nature.com
A conditionally replication-defective human cytomegalovirus (HCMV) vaccine, V160, was
shown to be safe and immunogenic in a two-part, double-blind, randomized, placebo …
shown to be safe and immunogenic in a two-part, double-blind, randomized, placebo …
Anti-Flavivirus Vaccines: Review of the Present Situation and Perspectives of Subunit Vaccines Produced in Escherichia coli
This article aims to review the present status of anti-flavivirus subunit vaccines, both those at
the experimental stage and those already available for clinical use. Aspects regarding …
the experimental stage and those already available for clinical use. Aspects regarding …
Precision arbovirus serology with a pan-arbovirus peptidome
WR Morgenlander, WN Chia, B Parra… - Nature …, 2024 - nature.com
Arthropod-borne viruses represent a crucial public health threat. Current arboviral serology
assays are either labor intensive or incapable of distinguishing closely related viruses, and …
assays are either labor intensive or incapable of distinguishing closely related viruses, and …