Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …

Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …

Methotrexate, a structural analogue of folic acid, is one of the most effective and extensively
used drugs for treating many kinds of cancer or severe and resistant forms of autoimmune …

The antitumor activity of disulfiram (DSF), a traditional US Food and Drug Administration-
approved drug for the treatment of “alcohol-dependence”, is Cu2+-dependent, but the …

Psoriasis is an inflammatory skin disease. Microneedle (MN) patches can improve psoriasis
treatment outcomes by increasing local drug content in the skin. As psoriasis frequently …

Chemotherapy remains one of the most prevailing regimens hitherto in the fight against
cancer, but its development has been being suffering from various fatal side effects …

Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical,
emotional and socioeconomic consequences. Despite advances in targeted biologic and …

Azobenzene-based molecules show unique trans-cis isomerization upon ultraviolet light
irradiation, which induce the change of polarity, crystallinity, stability, and binding affinity with …

Molecular photoswitches transform light energy into reversible structural changes. Their
combination with known pharmacophores often allows for photomodulation of the biological …

Photodynamic therapy (PDT)—which combines light, oxygen and photosensitizers (PS) to
generate reactive oxygen species—has emerged as an effective approach for targeted …