Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology

R Palmirotta, D Lovero, P Cafforio… - … in medical oncology, 2018 - journals.sagepub.com
Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits

SZ Shirejini, F Inci - Biotechnology Advances, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles released from various cells, and they can be
found in different bodily fluids. Exosomes have been utilized as biomarkers to diagnose …

Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics

ME Warkiani, BL Khoo, L Wu, AKP Tay, AAS Bhagat… - Nature protocols, 2016 - nature.com
Circulating tumor cells (CTCs) are rare cancer cells that are shed from primary or metastatic
tumors into the peripheral blood circulation. Phenotypic and genetic characterization of …

Technologies for circulating tumor cell separation from whole blood

P Bankó, SY Lee, V Nagygyörgy, M Zrínyi… - Journal of hematology & …, 2019 - Springer
The importance of early cancer diagnosis and improved cancer therapy has been clear for
years and has initiated worldwide research towards new possibilities in the care strategy of …

Modular microfluidics for life sciences

J Wu, H Fang, J Zhang, S Yan - Journal of Nanobiotechnology, 2023 - Springer
The advancement of microfluidics has enabled numerous discoveries and technologies in
life sciences. However, due to the lack of industry standards and configurability, the design …

Three-dimensional in vitro tumor models for cancer research and drug evaluation

X Xu, MC Farach-Carson, X Jia - Biotechnology advances, 2014 - Elsevier
Cancer occurs when cells acquire genomic instability and inflammation, produce abnormal
levels of epigenetic factors/proteins and tumor suppressors, reprogram the energy …

[PDF][PDF] Liquid biopsy for cancer: circulating tumor cells, circulating free DNA or exosomes?

W Zhang, W Xia, Z Lv, C Ni, Y Xin, L Yang - Cellular Physiology and …, 2017 - karger.com
Precision medicine and personalized medicine are based on the development of
biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry …

Microfluidic isolation of circulating tumor cell clusters by size and asymmetry

SH Au, J Edd, AE Stoddard, KHK Wong, F Fachin… - Scientific reports, 2017 - nature.com
Circulating tumor cell clusters (CTC clusters) are potent initiators of metastasis and
potentially useful clinical markers for patients with cancer. Although there are numerous …

[HTML][HTML] Advances in 3D bioprinting

Y Fang, Y Guo, T Liu, R Xu, S Mao, X Mo… - Chinese Journal of …, 2022 - Elsevier
Abstract Three-dimensional (3D) bioprinting has emerged as a promising approach for
engineering functional tissues and organs by layer-by-layer precise positioning of biological …