Endolysins are enzymes used by bacteriophages at the end of their replication cycle to
degrade the peptidoglycan of the bacterial host from within, resulting in cell lysis and release …

Streptococcus gallolyticus subsp. gallolyticus (Sg) has long been known to have a strong
association with colorectal cancer (CRC). This knowledge has important clinical …

Many Gram-positive spore-forming bacteria in the Firmicute phylum are important members
of the human commensal microbiota, which, in rare cases, cause opportunistic infections …

Intracellular pathogens have evolved diverse strategies to invade and survive within host
cells. Among the most studied facultative intracellular pathogens, Listeria monocytogenes is …

While anthrax is typically associated with bioterrorism, in many parts of the world the anthrax
bacillus (Bacillus anthracis) is endemic in soils, where it causes sporadic disease in …

Bacillus anthracis causes three forms of anthrax: inhalational, gastrointestinal, and
cutaneous. Anthrax is characterized by both toxemia, which is caused by secretion of …

Rifaximin is a poorly absorbed semisynthetic antibiotic derivative of rifampin licensed for use
in the treatment of traveler's diarrhea. Rifaximin reduces the symptoms of enteric infection …

Summary The Gram‐positive pathogen Bacillus anthracis causes anthrax, a fulminant and
lethal infection of mammals. Two large virulence plasmids, pXO1 and pXO2, harbour genes …

Bacillus anthracis is the causative agent of anthrax, and the spore form of the bacterium
represents the infectious particle introduced into a host. The spore is surrounded by an …

Since 1957, it has been proposed that the dissemination of inhalational anthrax required
spores to be transported from the lumena of the lungs into the lymphatic system. In 2002, this …