Leprosy is a chronic infectious disease whose evolution involves complex immune
mechanisms of the host that influence the clinical presentation of the disease. For many …

In recent years, advances in medical diagnosis and treatment have greatly attracted our
attention, whereas some rare diseases, such as leprosy, have not found a place in the …

Objectives Owing to difficulties in the clinical diagnosis of leprosy, several complementary
tests have been developed and used. The aim was to systematically summarize the …

Background 50% of leprosy patients suffer from episodes of Type 1/reversal reactions (RR)
and Type 2/Erythema Nodosum Leprosum (ENL) reactions which lead to morbidity and …

Leprosy, once considered as poor man's disease may cause severe neurological
complications and physical disabilities. Classification of leprosy depends upon the cell …

Leprosy is an ancient disease caused by gram positive, rod shaped bacilli called
Mycobacterium leprae. Patients present with varied clinico-pathological disease depending …

Discussion Leprosy is a chronic infectious disease caused by Mycobacterium leprae,
primarily affecting the skin and peripheral nerves. The diagnosis of leprosy is often …

Background Leprosy reactions, reversal reactions/RR and erythema nodosum
leprosum/ENL, can cause irreversible nerve damage, handicaps and deformities. The study …

Transcriptional profiling is a powerful tool to investigate and detect human diseases. In this
study, we used bulk RNA-sequencing (RNA-Seq) to compare the transcriptomes in skin …

Introduction Leprosy reactions, classified as type 1 and type 2 reactions, are acute clinical
conditions of exacerbation of localized or systemic inflammatory response inpatients with …