Emerging evidence indicates that gene products implicated in human cancers often cluster together in “hot spots” in protein-protein interaction (PPI) networks. Additionally, small sub …
Complex disease-associated single-nucleotide polymorphisms (SNPs) can create, destroy, or modify protein-coding sites. Cancer-associated genes have SNPs that affect gene …
For examining the intricate biological processes concerned with colorectal cancer (CRC), a systems biology approach integrating several biological components and other influencing …
Xeroderma pigmentosum (XP) is a rare genetic skin disorder caused due to the extreme sensitivity for ultraviolet (UV) radiations. On its exposure, DNA acquires damages leading to …
S Behl, A Sharma, P Suravajhala… - International Journal of …, 2020 - inderscienceonline.com
Microsatellite instability (MSI) is an error mechanism associated with DNA mismatch repair (MMR) system constituting a set of genes. If MMR fails, MSI may lead to various forms of …
Human beings are exposed to a variety of DNA damaging compounds on a regular basis, which can have an impact on their health and affect disease states. On the other hand, DNA …
TR Singh, P Suravajhala - Bioinformatics and Computational Biology - taylorfrancis.com
During the last two decades, bioinformatics has seen contemporaneous growth with massive genomic and proteomic data. A myriad of tools and servers have also been …
During the course of this project, I have been working as an Associate Analyst in the Market Analytics and Forecasting team at DelveInsight Business Research LLP which is a business …
T Katoch, PK Thakur, TR Singh - 2017 - ir.juit.ac.in
The two most important components of our project are modeling and simulation of the genes involved in the endometrial and ovarian cancer. The bottom up approach was used starting …