Enteroendocrine cells and gut hormones as potential targets in the crossroad of the gut-kidney axis communication

JAO Nery Neto, VY Yariwake, NOS Câmara… - Frontiers in …, 2023 - frontiersin.org
Recent studies suggest that disruptions in intestinal homeostasis, such as changes in gut
microbiota composition, infection, and inflammatory-related gut diseases, can be associated …

Naringenin is a potential anabolic treatment for bone loss by modulating osteogenesis, osteoclastogenesis, and macrophage polarization

X Zhou, Z Zhang, W Jiang, M Hu, Y Meng… - Frontiers in …, 2022 - frontiersin.org
Bone undergoes constant remodeling of formation by osteoblasts and resorption by
osteoclasts. In particular, macrophages have been reported to play an essential role in the …

[HTML][HTML] Substance P promote macrophage M2 polarization to attenuate secondary lymphedema by regulating NF-kB/NLRP3 signaling pathway

Z Zhou, X Sui, Z Cao, X Li, L Qing, J Tang - Peptides, 2023 - Elsevier
Secondary lymphedema often occurs after filariasis, trauma, lymph node dissection and
radiation therapy, which is manifested by infiltration of inflammatory cells and fibrosis …

[HTML][HTML] Involvement of neuronal tachykinin-like receptor at 86C in Drosophila disc repair via regulation of kynurenine metabolism

S Kashio, S Masuda, M Miura - Iscience, 2023 - cell.com
Neurons contribute to the regeneration of projected tissues; however, it remains unclear
whether they are involved in the non-innervated tissue regeneration. Herein, we showed …

The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing

Q Liu, M Yu, M Liao, Z Ran, X Tang, J Hu, B Su… - Journal of Molecular …, 2023 - Springer
Alpha-calcitonin gene-related peptide (αCGRP) and substance P (SP) are functionally
correlated sensory neuropeptides deeply involved in bone homeostasis. However, they are …

Chronic kidney disease has no impact on tear film substance p concentration in type 2 diabetes

K Asiedu, S Alotaibi, AV Krishnan, N Kwai, A Poynten… - Biomedicines, 2023 - mdpi.com
Purpose: The study aimed to ascertain the potential effects of chronic kidney disease (CKD)
on substance P concentration in the tear film of people with type 2 diabetes. Methods …

Wnt/β-catenin signaling pathway promotes renal ischemia–reperfusion injury through inducing oxidative stress and inflammation response

Q Dong, Y Jie, J Ma, C Li, T Xin… - Journal of Receptors and …, 2021 - Taylor & Francis
Oxidative stress and inflammation response have been found to be associated with renal
ischemia reperfusion (I/R) injury through an undefined mechanism. The aim of our study is to …

Efficacy of umbilical cord mesenchymal stem cell transfusion for the treatment of severe AKI: a protocol for a randomised controlled trial

Y Yang, J Gao, S Wang, W Wang, FL Zhu, X Wang… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Acute kidney injury (AKI) is a common and severe clinical problem that is
associated with high mortality, a long hospital stays and high healthcare resource …

Ultrasound enhances the therapeutic potential of mesenchymal stem cells wrapped in greater omentum for aristolochic acid nephropathy

Y Yang, X Geng, K Chi, C Liu, R Liu, X Chen… - Stem Cell Research & …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have been reported to promote
regeneration in both subjects with acute kidney injury (AKI) and chronic kidney disease …

协调组织修复: 控制有害和修复性中性粒细胞功能的分子途径

贺伟峰, 闫凌峰 - 中华烧伤与创面修复杂志, 2024 - zhsszz.xml-journal.net
中性粒细胞是最丰富的循环白细胞, 作为损伤组织和感染部位的第一反应者,
在愈合早期炎症反应中起着不可或缺的作用. 中性粒细胞通过吞噬和破坏病原体 …