In 2006, we established a scar/keloid-specialized unit in the Department of Plastic,
Reconstructive, and Aesthetic Surgery at Nippon Medical School (NMS) in Tokyo, Japan. In …

Background: In 2010, this Journal published my comprehensive review of the literature on
hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the …

Good and effective treatment in radiotherapy requires careful consideration of the complex
variables involved as well as critical assessment of the techniques. This new edition of an …

Significance: Hypertrophic scarring is a challenging issue for patients and clinicians. The
prevalence of hypertrophic scarring can be up to 70% after burns, and patients suffer from …

Keloid scars, characterized by abnormal fibroproliferation and excessive extracellular matrix
(ECM) production that extends beyond the original wound, often cause pruritus, pain, and …

Previous approaches to acne management have focused on the four main factors implicated
in acne, namely, androgen-mediated sebogenesis (considered integral to acne) …

Objective To provide a critical overview of current radiation modalities for keloid
management. Background Despite multimodal therapies, keloids that can develop following …

Background The mechanisms of hypertrophic scar formation and its tissue inflammation
remain unknown. Methods We collected 33 hypertrophic scar (HS) and 36 normal skin (NS) …

Introduction: Keloid is an abnormal proliferation of scar tissue that grows beyond the original
margins of the injury. Even after complete resection, recurrences are common and pose a …

Aim The goal of this study was to determine radiation oncologists' perspectives about the
utility and appropriateness of radiation therapy for keloid management in both adult and …