Research into human biotransformation and elimination systems continues to evolve.
Various clinical and in vivo studies have been undertaken to evaluate the effects of foods …

Liver disease is highly prevalent in the world. Oxidative stress (OS) and inflammation are the
most important pathogenetic events in liver diseases, regardless the different etiology and …

Liver fibrosis and hepatocellular carcinoma (HCC) have been worldwide threats nowadays.
Liver fibrosis is reversible in early stages but will develop precancerosis of HCC in cirrhotic …

Background: Astaxanthin is of carotenoids group which possess strong antioxidant
properties. The present study was conducted to evaluate the hepatoprotective effects of …

A molecular characterization of the main phytochemicals and antioxidant activity of Opuntia
robusta (OR) fruit extract was carried out, as well as an evaluation of its hepatoprotective …

In liver fibrosis, conversion of fibroblasts to profibrogenic myofibroblasts significantly drives
the development of the disease. A crucial role of cyclic adenosine monophosphate (cAMP) …

Liver fibrosis results from chronic damage to the liver in conjunction with various pathways
and is mediated by a complex microenvironment. Based on clinical observations, it is now …

The objective of this work was to investigate the effects of the methanol extracts of Gentiana
cruciata L. aerial parts (GCA) and roots (GCR) against carbon tetrachloride-induced liver …

Arsenic, a widely existing environmental contaminant, is recognized to be toxic to multiple
organs. Exposure to arsenic results in liver damage via excessive production of reactive …

This study aimed to investigate whether Opuntia spp-extracts protect against diclofenac (DF)-
induced hepatotoxicity. Rats were pretreated with Opuntia extracts, betanin (Bet) and N …