The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

Quantitative perfusion assessment using indocyanine green during surgery—current applications and recommendations for future use

P Van Den Hoven, J Osterkamp, N Nerup… - … Archives of Surgery, 2023 - Springer
Purpose Incorrect assessment of tissue perfusion carries a significant risk of complications in
surgery. The use of near-infrared (NIR) fluorescence imaging with Indocyanine Green (ICG) …

EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial

JG de Wit, J Vonk, FJ Voskuil, SAHJ de Visscher… - Nature …, 2023 - nature.com
Inadequate surgical margins occur frequently in oral squamous cell carcinoma surgery.
Fluorescence molecular imaging (FMI) has been explored for intraoperative margin …

3D-Printed Tumor Phantoms for Assessment of In Vivo Fluorescence Imaging Analysis Methods

EPM LaRochelle, SS Streeter, EA Littler… - Molecular imaging and …, 2023 - Springer
Purpose Interventional fluorescence imaging is increasingly being utilized to quantify cancer
biomarkers in both clinical and preclinical models, yet absolute quantification is complicated …

[HTML][HTML] Multispectral optoacoustic tomography of the human intestine–temporal precision and the influence of postprandial gastrointestinal blood flow

LP Paulus, AL Wagner, A Buehler, R Raming, J Jüngert… - Photoacoustics, 2023 - Elsevier
Multispectral optoacoustic tomography (MSOT) holds great promise as a non-invasive
diagnostic tool for inflammatory bowel diseases. Yet, reliability and the impact of …

Indocyanine green (ICG) and colorectal surgery: a literature review on qualitative and quantitative methods of usage

L Simion, S Ionescu, E Chitoran, V Rotaru, C Cirimbei… - Medicina, 2023 - mdpi.com
Background: Due to its many benefits, indocyanine green (ICG) has gained progressive
popularity in operating rooms (ORs) globally. This literature review examines its qualitative …

Improved intraoperative identification of close margins in oral squamous cell carcinoma resections using a dual aperture fluorescence ratio approach: first in-human …

CC Rounds, JG de Wit, J Vonk… - Journal of …, 2024 - spiedigitallibrary.org
Significance Surgical excision is the main treatment for solid tumors in oral squamous cell
carcinomas, where wide local excision (achieving a healthy tissue margin of> 5 mm around …

Why and how optical molecular imaging should further be catalyzed by nuclear medicine and molecular imaging: report from the EANM piloting group

J Vonk, R Dierckx, S Keereweer, AL Vahrmeijer… - European Journal of …, 2024 - Springer
European Journal of Nuclear Medicine and Molecular Imaging hurdles, it becomes
increasingly evident that the NM community could play a pivotal role in this process, as …

Dye-free visualisation of intestinal perfusion using laser speckle contrast imaging in laparoscopic surgery: a prospective, observational multi-centre study

W Heeman, J Calon, A van der Bilt, JPEN Pierie… - Surgical …, 2023 - Springer
Introduction Intraoperative perfusion imaging may help the surgeon in creating the intestinal
anastomoses in optimally perfused tissue. Laser speckle contrast imaging (LSCI) is such a …

Integration of 3D Fluorescence Imaging and Luminescent Thermometry with Core–Shell Engineered NaYF4:Nd3+/Yb3+/Ho3+ Nanoparticles

M Vinícius-Araújo, N Shrivastava… - Inorganic …, 2024 - ACS Publications
The design of rare-earth-doped upconversion/downshifting nanoparticles (NPs) for
theoretical use in nanomedicine has garnered considerable interest. Previous research has …