Blood viscosity is an important determinant of local flow characteristics, which exhibits shear
thinning behavior: it decreases exponentially with increasing shear rates. Both hematocrit …

Studies performed in the last decades have highlighted the need to better understand the
contribution of the endothelium, vascular function, oxidative stress, inflammation …

Sickle cell disease (SCD) is a genetic disorder, characterized by hemolytic anemia and vaso‐
occlusive crises (VOCs). Data on the global SCD impact on quality of life (QoL) from the …

This narrative review aims to highlight the current paradigm on pain management in sickle
cell vaso-occlusive crisis. It specifically examines the pathophysiologic mechanisms of sickle …

Sickle cell disease (SCD) is a recessive genetic blood disorder exhibiting abnormal blood
rheology. Polymerization of sickle hemoglobin, due to a point mutation in the β‐globin gene …

Although pulmonary hypertension, leg ulcers, priapism, stroke and glomerulopathy in sickle
cell anaemia (SCA) result from the adverse effects of chronic haemolysis on vascular …

To address the global burden of sickle cell disease (SCD) and the need for novel therapies,
the American Society of Hematology partnered with the US Food and Drug Administration to …

Cerebral vasculopathy is the most severe complication to affect children with sickle cell
anaemia and its pathophysiology is complex. Traditionally, small‐vessel occlusion by …

Pourtant, quand l'on tente de cerner de plus près la corruption en tant que concept, elle
semble s' évanouir. Si la corruption consiste à «se» vendre, n'est-elle pas au cœur des …

Hemorheological risk factors of acute chest syndrome and painful vaso-occlusive crisis in
children with sickle cell disease - PMC Back to Top Skip to main content NIH NLM Logo Access …