[HTML][HTML] An update on mesoporous silica nanoparticle applications in nanomedicine

E Rastegari, YJ Hsiao, WY Lai, YH Lai, TC Yang… - Pharmaceutics, 2021 - mdpi.com
The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …

Application of mesoporous silica nanoparticles in cancer therapy and delivery of repurposed anthelmintics for cancer therapy

M Koohi Moftakhari Esfahani, SE Alavi, PJ Cabot… - Pharmaceutics, 2022 - mdpi.com
This review focuses on the biomedical application of mesoporous silica nanoparticles
(MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and …

[HTML][HTML] An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment

CH Hsieh, HC Hsieh, FH Shih, PW Wang, LX Yang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Simultaneous targeting of both the tumor microenvironment and cancer cells by a single
nanomedicine has not been reported to date. Here, we report the dual properties of zero …

Anti-lung cancer effect of paclitaxel solid lipid nanoparticles delivery system with curcumin as co-loading partner in vitro and in vivo

C Pi, W Zhao, M Zeng, J Yuan, H Shen, K Li, Z Su… - Drug Delivery, 2022 - Taylor & Francis
The main aim of this study was to improve the therapeutic potential of a paclitaxel (PTX) and
curcumin (CU) combination regimen using solid lipid nanoparticles (SLNs). PTX and CU …

Near‐infrared‐II light induced mild hyperthermia activate cisplatin‐artemisinin nanoparticle for enhanced chemo/chemodynamic therapy and immunotherapy

G Xiong, D Huang, L Lu, X Luo, Y Wang, S Liu… - Small …, 2022 - Wiley Online Library
Chemodynamic therapy (CDT) is an effective cancer treatment that uses Fenton reaction to
induce cancer cell death. Current clinical applications of CDT are limited by the dependency …

[HTML][HTML] Natural biopolymers as smart coating materials of mesoporous silica nanoparticles for drug delivery

B Dumontel, V Conejo-Rodríguez, M Vallet-Regí… - Pharmaceutics, 2023 - mdpi.com
In recent years, the functionalization of mesoporous silica nanoparticles (MSNs) with
different types of responsive pore gatekeepers have shown great potential for the …

Sniping cancer stem cells with nanomaterials

WD Wang, YY Guo, ZL Yang, GL Su, ZJ Sun - ACS nano, 2023 - ACS Publications
Cancer stem cells (CSCs) drive tumor initiation, progression, and therapeutic resistance due
to their self-renewal and differentiation capabilities. Despite encouraging progress in cancer …

Recent updates in the polysaccharides-based Nano-biocarriers for drugs delivery and its application in diseases treatment: A review

J Zhang, P Zhan, H Tian - International Journal of Biological …, 2021 - Elsevier
With people's increasing awareness of diseases treatment, the researchers began to focus
on drug delivery to the exact site of action at the optimal rate. Some researchers have …

Injectable hydrogel imbibed with camptothecin-loaded mesoporous silica nanoparticles as an implantable sustained delivery depot for cancer therapy

JM Jung, YL Jung, SH Kim, DS Lee… - Journal of Colloid and …, 2023 - Elsevier
In recent years, injectable stimuli-sensitive hydrogels are employed as suitable drug delivery
carriers for the release of various anti-cancer drugs. However, large pore size of the …

Dendronized hyaluronic acid-docetaxel conjugate as a stimuli-responsive nano-agent for breast cancer therapy

W Wang, X Zhang, Z Li, D Pan, H Zhu, Z Gu… - Carbohydrate …, 2021 - Elsevier
To achieve target delivery of anti-tumor drugs with great biocompatibility into tumor tissues, a
stimuli-responsive dendronized hyaluronic acid (HA)-docetaxel conjugate (HA-DTX …