Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing

S Barrère-Lemaire, A Vincent… - Physiological …, 2024 - journals.physiology.org
Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains
the most common cause of heart failure. Reopening of the occluded artery, ie, reperfusion, is …

The effects of statins on dental and oral health: a review of preclinical and clinical studies

S Tahamtan, F Shirban, M Bagherniya… - Journal of translational …, 2020 - Springer
The statin family of drugs are safe and effective therapeutic agents for the treatment of
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …

Pleotropic effects of statins: the dilemma of wider utilization of statin

A Choudhary, U Rawat, P Kumar, P Mittal - The Egyptian Heart Journal, 2023 - Springer
Background Apart from reducing the circulating LDL-c and the number of cardiovascular
cases as well as fatalities, statins have auxiliary non–lipid-related or cholesterol …

How to hit mesenchymal stromal cells and make the tumor microenvironment immunostimulant rather than immunosuppressive

A Poggi, S Varesano, MR Zocchi - Frontiers in immunology, 2018 - frontiersin.org
Experimental evidence indicates that mesenchymal stromal cells (MSCs) may regulate
tumor microenvironment (TME). It is conceivable that the interaction with MSC can influence …

Advances and prospects in stem cells for cartilage regeneration

M Wang, Z Yuan, N Ma, C Hao, W Guo… - Stem Cells …, 2017 - Wiley Online Library
The histological features of cartilage call attention to the fact that cartilage has a little
capacity to repair itself owing to the lack of a blood supply, nerves, or lymphangion. Stem …

Therapeutic strategies for cell-based neovascularization in critical limb ischemia

M Samura, T Hosoyama, Y Takeuchi, K Ueno… - Journal of translational …, 2017 - Springer
Critical limb ischemia (CLI) causes severe ischemic rest pain, ulcer, and gangrene in the
lower limbs. In spite of angioplasty and surgery, CLI patients without suitable artery inflow or …

Statins in nonsurgical and surgical periodontal therapy. A systematic review and meta‐analysis of preclinical in vivo trials

K Bertl, I Steiner, N Pandis, K Buhlin… - Journal of …, 2018 - Wiley Online Library
The cholesterol‐lowering drugs, statins, possess anti‐inflammatory, antimicrobial and pro‐
osteogenic properties, and thus have been tested as an adjunct to periodontal treatment …

[HTML][HTML] Optimizing stem cells for cardiac repair: current status and new frontiers in regenerative cardiology

S Der Sarkissian, T Lévesque… - World journal of stem …, 2017 - ncbi.nlm.nih.gov
Cell therapy has the potential to improve healing of ischemic heart, repopulate injured
myocardium and restore cardiac function. The tremendous hope and potential of stem cell …

Statins: Complex outcomes but increasingly helpful treatment options for patients

N Mohammadkhani, S Gharbi, HF Rajani… - European Journal of …, 2019 - Elsevier
Statins are long known class of medicines and the most frequently prescribed drugs in
cardiovascular pharmacotherapy, widely ordered not only in patients suffering from …

The state of art of regenerative therapy in cardiovascular ischemic disease: biology, signaling pathways, and epigenetics of endothelial progenitor cells

F Perrotta, A Perna, K Komici, E Nigro, M Mollica… - Cells, 2020 - mdpi.com
Ischemic heart disease is currently a major cause of mortality and morbidity worldwide.
Nevertheless, the actual therapeutic scenario does not target myocardial cell regeneration …