The sympathetic nervous system (SNS) is known to play a pivotal role in short-and long-term
regulation of different functions of the cardiovascular system. In the past decades increasing …

The kidney is innervated with efferent sympathetic nerve fibers that directly contact the
vasculature, the renal tubules, and the juxtaglomerular granular cells. Via specific …

Background: The paraventricular nucleus of the hypothalamus (PVN) has emerged as one
of the most important autonomic control centers in the brain, with neurons playing essential …

Significance: The regulation of myocardial function by constitutive nitric oxide synthases
(NOS) is important for the maintenance of myocardial Ca2+ homeostasis, relaxation and …

The discovery in 1987 that endothelium-derived nitric oxide (NO) mediates the vasodilatory
effect of certain endothelium-dependent agonists1, 2 inaugurated the current huge field of …

Most forms of hypertension are associated with a wide variety of functional changes in the
hypothalamus. Alterations in the following substances are discussed: catecholamines …

The gaseous molecule nitric oxide (NO) plays an important role in cardiovascular
homeostasis. It plays this role by its action on both the central and peripheral autonomic …

The paraventricular nucleus of the hypothalamus (PVN) is an important site for autonomic
and endocrine homeostasis. The PVN integrates specific afferent stimuli to produce an …

The identification of nitric oxide (NO) as a gaseous, nonconventional neurotransmitter in the
central nervous system has led to an explosion of studies aimed at learning about the roles …

Elevated sympathetic nerve activity, strongly associated with cardiovascular disease, is
partly generated from the presympathetic neurons of the paraventricular nucleus of the …