Immunotherapy-based combination strategies for treatment of EGFR-TKI-resistant non-small-cell lung cancer

Y Chen, Z Chen, R Chen, C Fang, C Zhang, M Ji… - Future …, 2022 - Taylor & Francis
The rapid development of molecular targeted therapy brings hope to patients with advanced
non-small-cell lung cancer (NSCLC). However, drug resistance inevitably occurs during …

[HTML][HTML] Lung cancer in India

N Singh, S Agrawal, S Jiwnani, D Khosla… - Journal of Thoracic …, 2021 - Elsevier
India is a land of diversity with a motley of cultures, religions, languages, festivals, and ethnic
groups. The country's population as of 2020 is more than 1.38 billion, which accounts for …

Immunotherapy in small cell lung cancer treatment: a promising headway for future perspective

HK Walia, P Sharma, N Singh, S Sharma - Current Treatment Options in …, 2022 - Springer
Opinion statement Despite advancements in clinical research, both prognosis and treatment
for SCLC patients are still in the nascent stage. SCLC is a fatal disease with high tumor …

Real-world experience in treatment of patients with non-small-cell lung cancer with Braf or Cmet exon 14 skipping mutations

U Janzic, W Shalata, K Szymczak… - International Journal of …, 2023 - mdpi.com
BRAF and cMET exon 14 skipping are rare mutations of NSCLC. The treatment sequence in
these cases for the first and second line is not clear. An international registry was created for …

[HTML][HTML] Clinical efficacy and safety of individualized pembrolizumab administration based on pharmacokinetic in advanced non-small cell lung cancer: A prospective …

N Wang, L Zheng, M Li, X Hou, B Zhang, J Chen, S Li… - Lung Cancer, 2023 - Elsevier
Introduction Pembrolizumab is recommended with a fixed dose of 200 mg 3-weekly. We
performed this study to explore the clinical efficacy and safety of pharmacokinetic (PK) …

An ultra-long-acting L-asparaginase synergizes with an immune checkpoint inhibitor in starvation-immunotherapy of metastatic solid tumors

S Zhang, L Gong, Y Sun, F Zhang, W Gao - Biomaterials, 2025 - Elsevier
Metastasis stands as the primary contributor to mortality associated with tumors.
Chemotherapy and immunotherapy are frequently utilized in the management of metastatic …

Changes in the Histology of Lung Cancer in Northern Italy: Impact on Incidence and Mortality

L Mangone, F Marinelli, I Bisceglia, A Zambelli… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer is a heterogeneous group of diseases in both morphology
and molecular subtypes. There are two main histological categories of lung cancer: small …

Beyond first-line immunotherapy: potential therapeutic strategies based on different pattern progressions: oligo and systemic progression

A Prelaj, CC Pircher, G Massa, V Martelli, G Corrao… - Cancers, 2021 - mdpi.com
Simple Summary The aim of this innovative review is to highlight the treatment strategies
beyond immune-checkpoint inhibitor (ICI)-based first-line therapy failure according to …

[HTML][HTML] The international association for the study of lung cancer global survey on programmed death-ligand 1 testing for NSCLC

M Mino-Kenudson, N Le Stang, JB Daigneault… - Journal of Thoracic …, 2021 - Elsevier
Introduction Programmed death-ligand 1 (PD-L1) immunohistochemistry (IHC) is required to
determine the eligibility for pembrolizumab monotherapy in advanced NSCLC worldwide …

Systematic analysis of stress granule regulators-associated molecular subtypes predicts drug response, immune response, and prognosis in non-small cell lung …

D Wang, J Ao, Y Xiong, X Zhang… - Frontiers in cell and …, 2022 - frontiersin.org
Lung cancer has the world's second highest cancer incidence and second highest cancer-
related mortality rate. However, the mechanism underlying non-small cell lung cancer …