Cancer is a multifaceted pathology, where cellular and acellular players interact to drive
cancer progression and, in the worst-case, metastasis. The current methods to investigate …

The physiological environment of the intestine is characterized by its variegated
composition, numerous functions and unique dynamic conditions, making it challenging to …

Over the last few years, the intestine has been extensively studied using in vitro microfluidic
systems, commonly known as gut-on-a-chip (GOC) devices. This interest has been due not …

Conductive polymer hydrogels (CPHs) hold significant promise in broad applications, such
as bioelectronics and energy devices. Hitherto, the development of a facile and scalable …

Conductive hydrogels, a class of novel polymeric material that combine the electronic
conductivity of intrinsically conductive materials and diverse functionalities of hydrogels, are …

Conventional preclinical evaluation implemented in 2D monolayer cultures falls short with
multiorgan interactions, while animal systems lack the specificity of the human species …

The aim of this review is to provide a systematic design guideline to users, particularly
engineers interested in developing and deploying lung models, and biologists seeking to …

Mimicking the physiological or pathophysiological barrier function of endothelial and
epithelial cells is an essential consideration in organ-on-a-chip models of numerous tissues …

Gastrointestinal (GI) mucus plays a pivotal role in the tissue homoeostasis and functionality
of the gut. However, due to the shortage of affordable, realistic in vitro GI models with a …

Cell culture models of endothelial and epithelial barriers typically use porous membrane
inserts (eg, Transwell inserts) as a permeable substrate on which barrier cells are grown …