Riboswitches are structured noncoding RNA domains used by many bacteria to monitor the
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …

Riboswitches are structured noncoding RNA domains that selectively bind metabolites and
control gene expression (;;). Nearly all examples of the known riboswitches reside in …

More than 55 distinct classes of riboswitches that respond to small metabolites or elemental
ions have been experimentally validated to date. The ligands sensed by these riboswitches …

Riboswitches are commonly used by bacteria to detect a variety of metabolites and ions to
regulate gene expression. To date, nearly 40 different classes of riboswitches have been …

Sugars are essential molecules for all terrestrial biota working in many biological processes.
Ribose is particularly essential as a building block of RNA, which could have both stored …

Membraneless compartments, such as complex coacervates, have been hypothesized as
plausible prebiotic micro-compartments due to their ability to sequester RNA; however, their …

The impressive body of work on the major evolutionary transitions in the last 20 y calls for a
reconstruction of the theory although a 2D account (evolution of informational systems and …

High-affinity nucleic acid ligands for a protein were isolated by a procedure that depends on
alternate cycles of ligand selection from pools of variant sequences and amplification of the …

Subpopulations of RNA molecules that bind specifically to a variety of organic dyes have
been isolated from a population of random sequence RNA molecules. Roughly one in 1010 …

During evolution, there have been several major changes in the way that genetic information
is organized and transmitted from one generation to the next. These transitions include the …